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Identification of regeneration-associated genes in zebrafish by a ChIP-on-chip assay and its application to mammals.

Identification of regeneration-associated genes in zebrafish by a ChIP-on-chip assay and its application to mammals.
通过芯片上 ChIP 测定鉴定斑马鱼再生相关基因及其在哺乳动物中的应用。
批准号:
22300109
负责人:
KATO Satoru
金额:
$11.48万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010-04-01 至 2013-03-31

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中文摘要
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英文摘要
Regeneration-associated genes (RAGs) were cloned from axotomized zebrafish retina. HSP70 (a stress protein) and purpurin (a retinol-binding protein) were rapidly induced in the fish retina after optic nerve injury. HSP70 was involved in cell survival of injured retinal ganglion cells (RGCs), whereas purpurin was involved in neurite sprouting from injured RGCs. These RAGs could easily induce regrowth of axotomized optic nerve in adult rat.
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会议论文
A novel function of Factor XIII-A in nerve regeneration
XIII-A 因子在神经再生中的新功能
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Hayashi, Y., Sugitani K]
通讯作者: Sugitani K
DOI: 10.1007/978-1-4614-0631-0_84
发表时间: 2012-01-01
期刊: RETINAL DEGENERATIVE DISEASES
影响因子: --
作者: [Fujikawa, Chieko, Nagashima, Mikiko, Kato, Satoru]
通讯作者: Kato, Satoru
Reciprocal changes of factor XIII and retinal transglutaminase expressions in the fish retina during optic nerve regeneration
视神经再生过程中鱼视网膜中因子XIII和视网膜转谷氨酰胺酶表达的相互变化
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Nihei Y, Ito D, Okada Y, Akamatsu W, Yagi T, Yoshizaki T, Okano H, Suzuki N., 杉 谷 加 代]
通讯作者: 杉 谷 加 代
A distinct effect of two types of transglutaminase on fish optic nerve regeneration
两种转谷氨酰胺酶对鱼类视神经再生的不同作用
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Furumoto T, Fujita K, Toyoshima M, Zaiki K, Sahara S, Akita M, Ozawa N, Nakaoji K, Hamada K, Tamai K, Kaneda Y, Maeda A., 杉 谷 加 代]
通讯作者: 杉 谷 加 代
22
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