Functional analysis of key transcription factors regulating basic disease resistance in rice

植物对病原菌侵染有多种防御反应。在本研究中，我们对水稻中分别与抗菌蛋白表达和植物保卫素产生相关的关键转录因子OsWRKY53和OsTGAP1进行了功能分析。通过染色质免疫沉淀测序，对OsWRKY53和OsTGAP1的结合部位进行了全面鉴定。还获得了这两个转录因子的激活机制和相互作用因子的关键信息。

Plants respond to pathogen infection a variety of defense reactions. In this study, we investigatedfunctional analysis of the key transcription factors OsWRKY53 and OsTGAP1 that are, respectively,involved in expression of antimicrobial proteins and production of phytoalexins in rice. According to chromatin immunoprecipitation-sequencing, the binding sites of OsWRKY53 and OsTGAP1 were identified comprehensively . Key information on activation mechanisms and interacting factors of these two transcription factors were also obtained.