Metabolic status of sentinel lymph node from gastrointestinal cancer

胃肠癌前哨淋巴结的代谢状态

• 批准号: 22390263
• 负责人: KITAGAWA Yuko
• 金额: $ 12.06万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22390263/
• 关键词: MALDI-IMS; センチネルリンパ節; 消化器癌; 乳癌; メタボローム解析

Metabolic status of each intrinsic subtypes was analyzed by MALDI-IMS and CE-MS. It was revealed that triple negative breast cancer has the specific metabolic status which is related to the mechanisms of cell proliferation and the sensitivity against chem

采用MALDI-IMS和CE-MS技术分析了三阴性乳腺癌各内源性亚型的代谢状态，发现三阴性乳腺癌具有特异性的代谢状态，与细胞增殖机制和对化疗药物的敏感性有关。

项目成果

Antitumor effect of cetuximab in combination with S-1 in EGFR-amplified gastric cancer cells.

• DOI: 10.3892/ijo.2011.1279
• 发表时间: 2012-04
• 期刊: International journal of oncology
• 影响因子: 5.2
• 作者: Fukuda K;Saikawa Y;Takahashi M;Takahashi T;Wada N;Kawakubo H;Takeuchi H;Kitagawa Y
• 通讯作者: Kitagawa Y

Direct inhibition of the transforming growth factor-β pathway by protein-bound polysaccharide through inactivation of Smad2 signaling

• DOI: 10.1111/j.1349-7006.2011.02133.x
• 发表时间: 2012-02-01
• 期刊: CANCER SCIENCE
• 影响因子: 5.7
• 作者: Ono, Yoshihiro;Hayashida, Tetsu;Kitagawa, Yuko
• 通讯作者: Kitagawa, Yuko