Development of the ISVSr(irregular shaking and vibration stimulator) which is new physical therapy, and study of the content effective for the prevention of bone fracture by using it.

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The osteoporosis has a massive impact primarily on trabecular bone as a result of the postmenopausal decline in estrogen. The current study used a model of the decrease in bone density in ovariectomized mice to simulate postmenopausal women. Physical therapy to prevent a decrease in bone density was studied via stimulus in the form of rotation of a platform. Analysis of bone histomorphometry revealed lessening of the decrease in bone density of the lumbar vertebrae, a feat that the stimulus from conventional physical therapy had failed to achieve.With muscles that function as two-joint muscles such as the psoas major, differences exist in muscular hypertrophy, generation and differentiation between origin and insertion sides.