Influence of prior pandemic A(H1N1)2009 virus infection on invasion of MDCK cells by community-acquired MRSA
Influence of prior pandemic A(H1N1)2009 virus infection on invasion of MDCK cells by community-acquired MRSA
先前大流行A(H1N1)2009病毒感染对社区获得性MRSA侵袭MDCK细胞的影响
批准号：
22590514
负责人：
TAKAYAMA Yoko
金额：
$2.58万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2010
资助国家：
日本
项目状态：
已结题
起止时间：
2010 至 2012
中文摘要
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英文摘要
In this study, we investigated whether prior infection with pandemic A(H1N1)2009 virus (A(H1N1)pdm09) led to increased invasion of airway epithelial cells by CA-MRSA. We performed the gentamicin killing assay using Madin-Darby canine kidney (MDCK) cells and various bacteria to investigate whether prior A(H1N1)pdm09 infection led to increased invasion of these epithelial cells by CA-MRSA. We found that the invasion rate of two MRSA strains (ATCC BAA-1680 (USA 300) and ATCC BAA-1699 (USA 100)) into intact MDCK cell monolayers was 0.29±0.15% and 0.007±0.002%, respectively (p=3). In addition, the relative invasion rate of both ATCC BAA-1680 and ATCC BAA-1699 was significantly increased by prior A(H1N1)pdm09 infection of MDCK monolayers from 1±0.28 to 1.38±0.02 and from 1±0.24 to 1.73±0.29, respectively (p
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
市中感染型MRSAの気道上皮培養細胞への侵入性に関する検討
社区获得性MRSA侵入培养的气道上皮细胞能力的研究
社区获得性MRSA侵入培养的气道上皮细胞能力的研究
DOI：
--
发表时间：
2010
期刊：
影响因子：
--
作者：
[矢野寿一, 平潟洋一, Lynch SV, Kunishima H, 大島英敏, Yamashita H, 矢野寿一, 矢野寿一, 平潟洋一, 矢野寿一, 矢野寿一, 平潟洋一, 平潟洋一, 堀亨, Yano H, Arai K, Endo S, Yano H, 矢野寿一, Kanamori H, Kanamori H, 平潟洋一, 國島広之, 矢野寿一, 青柳哲史, 遠藤史郎, Kanamori H, Hatta M, Kanamori H, Kunishima H, Kanamori H, Yano H, Kuroda H, Kanamori H, 堀亨, Hirakata Y, 矢野寿一, 高山陽子]
通讯作者：
高山陽子
Anthropological Study on the Ideology of Chinese Characters in China Tourism.
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批准号：19720229
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项目类别：Grant-in-Aid for Young Scientists (B)
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资助金额：$1.22万
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财政年份：2007
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负责人：TAKAYAMA Yoko
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依托单位：
海外基金
