Protective effect of Kampo medicine on vascular endothelial functionin patients with metabolic syndrome
Protective effect of Kampo medicine on vascular endothelial functionin patients with metabolic syndrome
批准号:
22590649
负责人:
SHIMADA Yutaka
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
We clarified the improvement effect of keishibukuryogan, a traditional Japanese (Kampo) formula, on endothelial function in patients with metabolic syndrome-related factors by controlled clinical trial with cross-over design. In 49 patients who completed all the tests, the index for the evaluation of endothelial function (L_RHI) assessed by Endo-PAT2000 increased significantly, and the serum non-esterified fatty acid (NEFA), malondialdehyde (MDA) and soluble vascular cell adhesion molecule-1(sVCAM-1) decreased significantly after 4 weeks of KBG-treatment period, and the changes of L_RHI, NEFA and MDA in the treatment period were significantly different from those in the control period
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メタボリックシンドローム関連因子を有する患者の血管内皮機能に及ぼす桂枝茯苓丸の効果:比較臨床試験
庆志服药丸对代谢综合征相关因素患者血管内皮功能影响的比较临床研究
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[永田 豊, 後藤博三, 井上博喜, 野上達也, 藤本 誠, 引網宏彰, 柴原直利, 長坂和彦, 嶋田 豊]
通讯作者:
嶋田 豊
メタボリックシンドローム関連因子を有する患者の血管内皮機能に及ぼす桂枝茯苓丸の効果:比較臨床試験
庆志服药丸对代谢综合征相关因素患者血管内皮功能影响的比较临床研究
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[M Kano, T Tomoko, et al, 永田 豊]
通讯作者:
永田 豊
Research on the treatment of esophageal cancer with anti-human fibroblast growth factor receptor like-1
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批准号:26293302
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.4万
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财政年份:2014
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负责人:SHIMADA Yutaka
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依托单位:
Detection of gastrointestinal cancer biomarkers by next-generation mass spectrometry and comprehensive gene expression analysis
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批准号:23390320
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
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财政年份:2011
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负责人:SHIMADA Yutaka
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依托单位:
Research for the establishment of pluripotent stem cells from normal human culture cells and tissue engineering
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批准号:22659228
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.04万
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财政年份:2010
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负责人:SHIMADA Yutaka
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依托单位:
The expression and function of microRNA in esophageal cancer cells and normal esophageal epithelial cells
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批准号:19390356
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2007
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负责人:SHIMADA Yutaka
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依托单位:
Research for esophageal carcinogenesis and proliferation, by characterization of cancer stem cells and analysis of the inactivation mechanism for suppressor genes in normal esophageal epithelial cells.
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批准号:17390363
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.79万
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财政年份:2005
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负责人:SHIMADA Yutaka
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依托单位:
Neuroprotective effect of Kampo medicine against brain ischemia and its mode of action
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批准号:16590556
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2004
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负责人:SHIMADA Yutaka
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依托单位:
ELECTROMAGNETIC PROPERTIES AND APPLICATION TO MICRO-EMC OF THE METAL-OXIDE COMPOSITE FILMS WITH A FIBER LIKE NANO-STRUCTURE
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批准号:15360158
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.54万
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财政年份:2003
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负责人:SHIMADA Yutaka
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依托单位:
Research for esophageal carcinogenesis and differentiation induction therapy based on normal esophageal epithelial cells and esophageal stem cells
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批准号:14370385
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.47万
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财政年份:2002
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负责人:SHIMADA Yutaka
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依托单位:
Construction of educational global standardin Kampo Medicine
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批准号:13470502
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.25万
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财政年份:2001
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负责人:SHIMADA Yutaka
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依托单位:
Molecular analysis and application of differentiation induction therapy with intra-nuclear receptor and intra-cellular signal transduction factor
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批准号:12470259
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.59万
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财政年份:2000
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负责人:SHIMADA Yutaka
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依托单位:
Growth arrest signal in esophageal cancer. Biological significance and clinical implication of EGF-STAT signal transduction system.
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批准号:10470241
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.3万
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财政年份:1998
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负责人:SHIMADA Yutaka
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依托单位:
Fundamental study on gene therapy for diseased myocardium by introduction of myogenetic genes into fibroblasts
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批准号:10557001
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.63万
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财政年份:1998
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负责人:SHIMADA Yutaka
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依托单位:
Gene expression of muscle proteins and molecular mechanisms of contractile structure formation
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批准号:09670002
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1997
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负责人:SHIMADA Yutaka
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依托单位:
Synthesis of metal alloy particles with high magnetic surface anisotropy and development of new functions
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批准号:09450231
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.32万
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财政年份:1997
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负责人:SHIMADA Yutaka
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依托单位:
Research on the prediction of hematogenous metastasis and recurrence of hepatocellular carcinoma, pancreatic carcinoma, gastric carcinoma and esophageal carcinoma. (Detection of circulating AFPmRNA,CEAmRNA and Cytokeratin mRNA)
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批准号:09671301
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:1997
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负责人:SHIMADA Yutaka
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依托单位:
SYNTHESIS PROCESS AND GIANT MAGNETIZATION OF INTERSTITIAL TYPE (Fe、Co)-(B、C、N) SINGLE CRYSTALS
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批准号:07455273
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.54万
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财政年份:1995
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负责人:SHIMADA Yutaka
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依托单位:
Analysis of Cell Cycle Related Gene and Cell Culture in Esophageal Cancer. (Carcinogenesis, Tumor Progression and Prognostic Factor)
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批准号:07671386
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.6万
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财政年份:1995
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负责人:SHIMADA Yutaka
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依托单位:
Cardiac morphogenesis and myofibrillogenesis
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批准号:06044037
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$5.25万
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财政年份:1994
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负责人:SHIMADA Yutaka
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依托单位:
Molecular and cellular biology of dynamics and mechanisms of myofibrillogenesis
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批准号:06670010
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:SHIMADA Yutaka
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依托单位:
Regeneration of muscle fibers after myoblast injection into dystrophic muscle
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批准号:05557001
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$5.25万
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财政年份:1993
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负责人:SHIMADA Yutaka
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依托单位:
海外基金