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Analysis of anti-tumor activity and anti-virus effect after allogeneic hematopoietic stem cell transplantation for patients with ATL

Analysis of anti-tumor activity and anti-virus effect after allogeneic hematopoietic stem cell transplantation for patients with ATL
ATL患者异基因造血干细胞移植后抗肿瘤及抗病毒作用分析
批准号:
22591065
负责人:
FUKUSHIMA Takuya
金额:
$1.58万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
Among long-term survivors with ATL treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT) in Nagasaki prefecture, there was no patient with undetected level of HTLV-1 proviral DNA load except one patient of our previous report. However, we found an efficacy of all-HSCT for ATL patients with central nervous system involvement and feasibility of cord blood transplantation for patients with ATL, contributed by graft-versus-ATL (GvATL) effect of immunocompetent cells. And also we showed that donor lymphocyte infusion had effectiveness for some relapsed patients with ATL after allo-HSCT. In our analysis we find that GvATL effect work for anti-tumor activity in allo-HSCT for patients with ATL.
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会议论文
長崎県における成人T細胞白血病・リンパ腫(ATL)に対する濟帯血移植(CBT)の治療成績
长崎县脐带血移植(CBT)治疗成人T细胞白血病/淋巴瘤(ATL)的结果
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Murakami, Y., N. Inoue, T. Shichishima, R. Ohta, H. Noji, Y. Maeda, J. Nishimura, Y. Kanakura and T. Kinoshita, 加藤光次, 笠原 浩二, 福島卓也 森内幸美 吉田真一郎 糸永英弘 田口潤 宮崎泰司, 尾崎 司, 加藤光次, 福島卓也]
通讯作者: 福島卓也
Gastric involvement by mantle cell lymphoma observed by magnified endoscopy with narrow-band imaging.
通过窄带成像放大内窥镜观察到套细胞淋巴瘤累及胃。
DOI: 10.1016/j.gie.2011.10.018
发表时间: 2012
期刊: Gastrointest Endosc.
影响因子: --
作者: [Norimura D, et al]
通讯作者: et al
DOI: 10.1007/s12185-011-0935-3
发表时间: 2011-10-01
期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY
影响因子: 2.1
作者: [Fukushima, Takuya, Taguchi, Jun, Miyazaki, Yasushi]
通讯作者: Miyazaki, Yasushi
Lymphoma study group of JCOG
JCOG淋巴瘤研究组
DOI: 10.1093/jjco/hyr168
发表时间: 2012
期刊: Jpn J Clin Oncol
影响因子: 2.4
作者: [Tsukasaki K, Tobinai K, Hotta T, Shimoyama M]
通讯作者: Shimoyama M
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