Trial of the pulmonary ischemic re-perfusion injury suppression by the suppression of the mitochondrial injury

影响肺移植结果的主要因素是慢性切除。认为移植后缺血再灌注损伤的存在是其原因之一。在再灌注时出现强烈的线粒体损伤。线粒体损伤（PT：渗透性转变）是通过再灌注时的氧化应激得到的，并且在那时，大量线粒体蛋白质泄漏。线粒体蛋白流出被氢气吸入抑制，肺缺血再灌注被抑制。

The main factor affecting the outcome of the lung transplantation is chronic resection. It is said that one of the causesis the presence of the ischemia re-perfusion injury after transplantation. An intense mitochondrial injury appears at the time of re-perfusion. Mitochondrial injury (PT: permeability transition) is derived through oxidation stress at the time of re-perfusion, and at that time, a large quantity of mitochondrial protein leaks. Mitochondrial protein outflow was suppressed by the hydrogen inhalation, and a pulmonary ischemia re-perfusion was suppressed.