Transcutaneous immunization induces antigen specific mucosal and syatemic immune responses in mice
Transcutaneous immunization induces antigen specific mucosal and syatemic immune responses in mice
批准号:
22591911
负责人:
MASEDA Yoshiko
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In order to investigate the differences in the immune responsesamong several mucosal immunizations, mice were immunized with phosphorylcholine (PC) together with cholera toxin (CT) as mucosal adjuvant intranasally and transcutaneously, and the mucosal as well as systemic immune responses were compared. PC-specific IgA antibody titers in saliva and nasal wash were increased by intaranasal as well as transcutaneous immunization to the same levels.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Intranasal immunization of with Phosphorylcholine reduced type Iallergic responses in mice. 24thCongrress of the European Rhinologic Society
磷酸胆碱的鼻内免疫减少了小鼠的类型过敏反应。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[石川征司, 楯谷一郎, 早坂孝宏, 瀧澤義徳, 大野 覚, 児嶋 剛, 木谷芳晴, 北村守正, 平野 滋, 瀬藤光利, 伊藤壽一, Yoshinori Matsuwaki, Y. Kurono]
通讯作者:
Y. Kurono
コレラトキシン経皮免疫による粘膜免疫応答
霍乱毒素透皮免疫引起的粘膜免疫反应
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[北村 拓朗 , 宮崎 総一郎 , 鈴木 秀明, 牧瀬高穂, Yuichi Kurono, 永野広海, 宮下圭一, Keiichi Miyashita, 永野広海, 永野広海, 黒野祐一, 永野広海]
通讯作者:
永野広海
Transcutaneous immunization with cholera toxin in BALB/C mice.
BALB/C 小鼠霍乱毒素经皮免疫。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[石川征司, 楯谷一郎, 大野覚, 児嶋剛, 木谷芳晴, 瀧澤義徳, 早坂孝宏, 北村守正, 平野滋, 瀬藤光利, 伊藤壽一, 山内一真, H. Nagano]
通讯作者:
H. Nagano
Immunological difference in upper respiratory tracts between sublingual and intranasal immunization
舌下和鼻内免疫上呼吸道免疫学差异
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[山内一真, 山中昇, 永野広海, 山内一真, Yoshiko Hayamizu]
通讯作者:
Yoshiko Hayamizu
Diversity of mucosal immune responses in upper respiratory airways and the suitability of mucosal vaccines
上呼吸道粘膜免疫反应的多样性和粘膜疫苗的适用性
DOI:
--
发表时间:
2012
期刊:
Clinical & Experimental Allergy Reviews
影响因子:
--
作者:
[Matsuwaki Y, Wada K, White T, Moriyama H, Kita H, Y. Kurono]
通讯作者:
Y. Kurono
共 13 条
Development of nasal boost immunization with phosphorylcholine as a novel pneumococcal vaccination program
-
批准号:17K11335
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2017
-
负责人:MASEDA Yoshiko
-
依托单位:
海外基金