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The role of autophagy in a tooth development

The role of autophagy in a tooth development
自噬在牙齿发育中的作用
批准号:
22792052
负责人:
YANAGITA Takeshi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
翻译
本研究旨在明确自噬在硬组织尤其是牙齿发育过程中的作用。首先,我们发现野生型小鼠的牙齿发育与ATG5 KO(自噬阻断)小鼠的牙齿发育存在差异。另一方面,我们在实验过程中也注意到自噬对骨组织发育的影响大于对牙齿发育的影响。这些结果发表在学术期刊和会议上。
英文摘要
This study is to be clear the role of autophagy in the process of hard tissue development, especially tooth. At first, we found the difference between tooth development of wild type mouse and that of ATG5 KO(autophagy blocked) mice.In other hand, we also noticed that the influence of autophagy is larger in bone tissue development rather than tooth development in my experiment process. These results were presented on academic journals and meetings.
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DOI: 10.1159/000322557
发表时间: 2011-01
期刊: Cells Tissues Organs
影响因子: 2.7
作者: [Y. Shintaku;Takashi Murakami;T. Yanagita;N. Kawanabe;T. Fukunaga;Kiyomi Matsuzaki;S. Uematsu;Yasuhiro Yoshida;H. Kamioka;T. Takano-Yamamoto;K. Takada;T. Yamashiro]
通讯作者: Y. Shintaku;Takashi Murakami;T. Yanagita;N. Kawanabe;T. Fukunaga;Kiyomi Matsuzaki;S. Uematsu;Yasuhiro Yoshida;H. Kamioka;T. Takano-Yamamoto;K. Takada;T. Yamashiro
Do epigenetics influences the form of a mandibular beyond the generation.
  • 批准号:
    24792284
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.75万
  • 财政年份:
    2012
  • 负责人:
    YANAGITA Takeshi
  • 依托单位:
海外基金