Development of cryoprotectant for human cell

为了防止造血干细胞的冷冻损伤，加入冷冻保护剂DMSO。由于DMSO会引起副作用，因此开发了一种新的冷冻保护剂。新的冷冻保护剂的能力不劣于DMSO的能力，因为使用新的冷冻保护剂进行冷冻保存的造血干细胞产生的集落数量与使用DMSO的情况相当。由于大鼠体内不会产生有害分子，因此预期新冷冻保护剂的毒性较低。

In order to prevent freezing damage for the hematopoietic stem cell, a cryoprotectant DMSO was added. Since side effects are caused by DMSO, a new cryoprotectant was developed. The ability of the new cryoprotectant is not inferior to that of DMSO since the number of the colonies generated by the hematopoietic stem cell where freezing preservation is carried out using the new cryoprotectant is equivalent to the case using DMSO. Since harmful molecules were not produced in the body of a rat, the toxicity of the new cryoprotectant is expected to be low.