Isolation and characterization of genes involved in the abnormalities of mitosis and nuclear morphology found in myelodysplastic syndromes.
Isolation and characterization of genes involved in the abnormalities of mitosis and nuclear morphology found in myelodysplastic syndromes.
批准号:
22659181
负责人:
INABA Toshiya
金额:
$2.01万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The aim of this study is isolation and characterization of genes involved in the abnormalities of mitosis and nuclear morphology frequently found in myelodysplastic syndromes(MDS). We identified Miki and CG-NAP as crucial members of the transportation system for pericentriolar materials(Mol. Cell), and dynactin-3 that maintains centrosome function in the metaphase(JBC).
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Analysis of epigenetic changes by 5-Azacitidine that induces erythroid differentiation using a next generation sequencer
使用下一代测序仪分析 5-阿扎胞苷诱导红细胞分化的表观遗传变化
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[井上優希, 呂軍, 幸谷愛, 松井啓隆]
通讯作者:
松井啓隆
(2011) Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo.
(2011) 体内野生型克隆快速出现特拉匹韦抗性丙型肝炎病毒株。
DOI:
--
发表时间:
2011
期刊:
Hepatology
影响因子:
13.5
作者:
[Hiraga, N., Imamura, M., Abe, H., Hayes, C. N., Kono, T., Onishi, M., Tsuge, M., Takahashi, S., Ochi, H., Iwao, E., Kamiya, N., Yamada, I., Tateno, C., Yoshizato, K., Matsui, H., Kanai, A., Inaba, T., Tanaka, S., and Chayama, K.]
通讯作者:
K.
a candidate-7/ 7q-responsible gene product, downregulates cytokine signals by facilitating formation of early endosome
候选 7/ 7q 相关基因产物,通过促进早期内体的形成来下调细胞因子信号
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Matsui, H. Titan(Samd9L)]
通讯作者:
H. Titan(Samd9L)
DOI:
10.1038/leu.2012.146
发表时间:
2012-12
期刊:
Leukemia
影响因子:
11.4
作者:
[Takeshi Ueda;M. Sanada;H. Matsui;N. Yamasaki;Z. Honda;L. Shih;H. Mori;T. Inaba;S. Ogawa;H. Honda]
通讯作者:
Takeshi Ueda;M. Sanada;H. Matsui;N. Yamasaki;Z. Honda;L. Shih;H. Mori;T. Inaba;S. Ogawa;H. Honda
(2011) The dynactin complex maintains the integrity of metaphasic centrosomes to ensure transition to anaphase
(2011) dynactin 复合物维持中期中心体的完整性,以确保向后期的过渡
DOI:
--
发表时间:
2011
期刊:
J. Biol. Chem
影响因子:
--
作者:
[Ozaki, Y., Matsui, H., Nagamachi, A., Asou, H., Aki, D., and Inaba, T.]
通讯作者:
T.
共 36 条
Roles of impairment of centrosome maturation in leukemogenesis
-
批准号:23390253
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.31万
-
财政年份:2011
-
负责人:INABA Toshiya
-
依托单位:
Functional analysis of candidate responsible genes for 7q deletion in MDS/AML
-
批准号:20390271
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.9万
-
财政年份:2008
-
负责人:INABA Toshiya
-
依托单位:
Isolation and characterization of candidate myeloid tumor-suppressor genes on the long arm of chromosome7.
-
批准号:18390284
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2006
-
负责人:INABA Toshiya
-
依托单位:
Analysis of expression control of the Bim gene.
-
批准号:16390279
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.51万
-
财政年份:2004
-
负责人:INABA Toshiya
-
依托单位:
Analysis of the Bim/Dlc protein complex regulating the survival of hematopoietic cells under the control of cytokines.
-
批准号:14370303
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.45万
-
财政年份:2002
-
负责人:INABA Toshiya
-
依托单位:
Functional analysis of the Bim/DLC complex in apoptosis regulation of hematopoietic progenitors
-
批准号:12470205
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$2.69万
-
财政年份:2000
-
负责人:INABA Toshiya
-
依托单位:
TEL-AML1融合転写調節因子の発癌機序の分析
-
批准号:10670965
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:1998
-
负责人:INABA Toshiya
-
依托单位:
海外基金