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Isolation and characterization of genes involved in the abnormalities of mitosis and nuclear morphology found in myelodysplastic syndromes.

Isolation and characterization of genes involved in the abnormalities of mitosis and nuclear morphology found in myelodysplastic syndromes.
骨髓增生异常综合征中涉及有丝分裂和核形态异常的基因的分离和表征。
批准号:
22659181
负责人:
INABA Toshiya
金额:
$2.01万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
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英文摘要
The aim of this study is isolation and characterization of genes involved in the abnormalities of mitosis and nuclear morphology frequently found in myelodysplastic syndromes(MDS). We identified Miki and CG-NAP as crucial members of the transportation system for pericentriolar materials(Mol. Cell), and dynactin-3 that maintains centrosome function in the metaphase(JBC).
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Analysis of epigenetic changes by 5-Azacitidine that induces erythroid differentiation using a next generation sequencer
使用下一代测序仪分析 5-阿扎胞苷诱导红细胞分化的表观遗传变化
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [井上優希, 呂軍, 幸谷愛, 松井啓隆]
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影响因子: 13.5
作者: [Hiraga, N., Imamura, M., Abe, H., Hayes, C. N., Kono, T., Onishi, M., Tsuge, M., Takahashi, S., Ochi, H., Iwao, E., Kamiya, N., Yamada, I., Tateno, C., Yoshizato, K., Matsui, H., Kanai, A., Inaba, T., Tanaka, S., and Chayama, K.]
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