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Urine metabolomics analysis for autistic spectrum disorder

Urine metabolomics analysis for autistic spectrum disorder
自闭症谱系障碍的尿液代谢组学分析
批准号:
22659211
负责人:
MINABE Yoshio
金额:
$1.98万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
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英文摘要
Because of its characteristics and simple non-invasive methods of collection, urine is particularly suited for metabolomic analysis even in young children. We explore urine fatty acid metabolic substance as a biomarker for autism spectrum disorder. In 32 ASD children and 24 typically developing(TD) young children(3-7 years old), 7 fatty acid metabolic substances(i. e., myristic acid, palmitic acid, linoleic acid, oleic acid, stearic acid, arachidic acid, behenic acid) in urine were quantified using gas chromatography. mass spectrometry. As a result, there were no significant differences in these concentrations between ASD and TD children. In addition, there were no significant correlations between cognitive performances and these concentrations.
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会议论文
脳とこころのプライマリ・ケア第4巻:子どもの発達と行動:双極性障害
大脑和精神初级保健第 4 卷:儿童发育和行为:双相情感障碍
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Anitha A, Nakamura K*, Yamada K, Suda S, Thanseem I, Tsuiji M, Iwayama Y, Hattori E, Toyota T, Miyachi T, Iwata Y, Suzuki K, Matsuzaki H, Kawai M, Sekine Y, Tsuchiva K, Sugihara G, Ouchi Y, Sugiyama T, Koizumi K, Higashida H, Takei N Yoshikawa T, Mori N., 菊池尚美,林義剛,篠崎たき子,楯林義孝, 福田正人, 棟居俊夫]
通讯作者: 棟居俊夫
Lateralized theta wave MEG coherence and language performance in 2- to 5-year-old children
2 至 5 岁儿童的侧化 theta 波 MEG 一致性和语言表现
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [上原徹, 須田真史, 福田正人, 三國雅彦, Nishioka Masaki, 菊知充]
通讯作者: 菊知充
2~5歳児の脳内機能結合と言語発達、そして広汎性発達障害早期診断への試み
2至5岁儿童的大脑功能连接和语言发展,以及广泛性发育障碍的早期诊断尝试
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Bundo Miki, Sunaga Fumiko, Ueda Junko, Kasai Kiyoto, Kato Tadafumi, Iwamoto Kazuya., 菊知充]
通讯作者: 菊知充
双極性障害子どもの心の診療シリーズ4:子どもの不安障害と抑うつ
双相情感障碍儿童心理保健系列4:儿童焦虑症和抑郁症
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [花元克巳, 迫田晃弘, 川辺睦, 片岡隆浩, 山岡聖典, 大久保善朗, 棟居俊夫]
通讯作者: 棟居俊夫
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