Monitoring of the blood anesthetics gas levels using interference enhanced reflection method

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Although the monitoring of blood anesthetic gas levels is an important for the safety of general anesthesia, no bedside monitoring method was found. We tested to monitor its levels using the interference enhanced reflection method with head space technique. It could get a quick response to the blood levels of isoflurane (0-5%), sevoflurane(0-5%) and desflurane(0-18%). Additionally, it allowed to monitor by only 1 ml blood sample volume by improving the head space technique.