Monitoring of the blood anesthetics gas levels using interference enhanced reflection method

血麻醉气体浓度的监测对全身麻醉的安全性有重要意义，但目前尚无床旁监测方法，我们采用顶空技术，采用干涉增强反射法监测血麻醉气体浓度。对异氟醚（0-5%）、七氟醚（0-5%）和地氟醚（0-18%）的血药浓度反应迅速。此外，通过改进顶空技术，仅允许监测1 ml血样体积。

Although the monitoring of blood anesthetic gas levels is an important for the safety of general anesthesia, no bedside monitoring method was found. We tested to monitor its levels using the interference enhanced reflection method with head space technique. It could get a quick response to the blood levels of isoflurane (0-5%), sevoflurane(0-5%) and desflurane(0-18%). Additionally, it allowed to monitor by only 1 ml blood sample volume by improving the head space technique.