In vitro study on comparison of epigenetic alteration patterns between periodontitis and a particular type of cancer models
In vitro study on comparison of epigenetic alteration patterns between periodontitis and a particular type of cancer models
批准号:
22659381
负责人:
KUBONIWA Masae
金额:
$2.09万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
To assess influences of Porphyromonas gingivalis infection on p53 and MDM2(p53 E3 ubiquitin protein ligase) expression, western blot analyses were performed. The results indicated that P. gingivalis mild infection activated MDM2, and that resulted in p53 reduction. Furthermore, impaired p53 accelerated the glycolysis pathway in infected gingival epithelial cells in the same manner as in cancer cells.
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DOI:
10.1586/epr.12.16
发表时间:
2012-06
期刊:
Expert review of proteomics
影响因子:
3.4
作者:
[Kuboniwa M, Tribble GD, Hendrickson EL, Amano A, Lamont RJ, Hackett M]
通讯作者:
Hackett M
マルチオミクスによる口腔感染症の分子基盤解析
使用多组学进行口腔感染的分子基础分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[久保庭雅恵, 天野敦雄]
通讯作者:
天野敦雄
Role of 4-aminobenzoate in interspecies communication
4-氨基苯甲酸酯在种间通讯中的作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kuboniwa M, Chawla A, Hashino E, Nagata H, Amano A, Hackett M, Lamont RJ, Shizukuishi S]
通讯作者:
Shizukuishi S
Chapter "Genotyping of periodontal anaerobic bacteria in relationship to pathogenesis", in "Molecular Typing in Bacterial Infections"
“细菌感染的分子分型”中的“牙周厌氧菌的基因分型与发病机制的关系”一章
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Amano A, Takeuchi H, Furuta N, 山本裕美子, 片岡宏介, Amano A, Amano A, 福井誠, 山口幹代, Baatarjav T., 天野敦雄, 久保庭雅恵, 片岡宏介, Kuboniwa M.]
通讯作者:
Kuboniwa M.
メタボロミクス解析によるエリスリトール存在下でのPorphyromonas gingivalis代謝プロファイルの検討
通过代谢组学分析检查赤藓糖醇存在下牙龈卟啉单胞菌的代谢特征
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kumasawa, K. Nakamura, H. Matsuzaki, T. Masaki, H. Koyama, S. Tsutsui, T. Kuroda, S. Kimura, T., Taiji Ogawa, 橋野恵衣,久保庭雅恵,黒田裕美子,前田和彦,小島美樹,永田英樹,天野敦雄]
通讯作者:
橋野恵衣,久保庭雅恵,黒田裕美子,前田和彦,小島美樹,永田英樹,天野敦雄
共 36 条
Development of a novel method to prevent an ecological shift in oral polymicrobial biofilms by using bacteriophage therapy.
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批准号:15H05057
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.32万
-
财政年份:2015
-
负责人:KUBONIWA Masae
-
依托单位:
Molecular basis of phenotype alteration between planktonic and biofilm in Porphyromonas gingivalis
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批准号:24593150
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
-
财政年份:2012
-
负责人:KUBONIWA Masae
-
依托单位:
Proteomics of Porphyromonas gingivalis within a model oral microbial community
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批准号:20592453
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2008
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负责人:KUBONIWA Masae
-
依托单位:
Identification of Streptoooocus gordoniigenes involved in recruiting Porphyromonas gingivatiscens into a multispecies biofilm
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批准号:18592276
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.39万
-
财政年份:2006
-
负责人:KUBONIWA Masae
-
依托单位:
海外基金