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Cholesterol metabolite-dependent regulation of synaptic development

Cholesterol metabolite-dependent regulation of synaptic development
突触发育的胆固醇代谢依赖性调节
批准号:
22700393
负责人:
SUZUKI Shingo
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
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英文摘要
Our previous study found that BDNF induced the synthesis of 24-hydroxycholesterol(24HC). However the roles of 24HC on CNS are not known. To better understand, we here investigate the effect of 24HC on primary neurons or astrocytes. The results indicated a possibility that, while 24HC was not involved in the BDNF-dependent effect on synapse development and dendritic morphology, 24HC did transduce the feedback signal to suppress the effect of BDNF.
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BDNF regulated Cholesterol homeostasis in CNS neurons
BDNF 调节 CNS 神经元中的胆固醇稳态
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [S. Suzuki, H. Qiu, T. Kasama, C. Itami, K. Kiyosue, M. Kojima, K. Tanaka]
通讯作者: K. Tanaka
「BDNFによるニューロンのコレステロール合成誘導とプレシナプス蛋白質のラフトへの移動
“BDNF 诱导神经元中的胆固醇合成以及突触前蛋白向筏的运动”
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [横山一剛, 手塚徹, 山梨裕司, 鈴木辰吾]
通讯作者: 鈴木辰吾
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [横山一剛, 手塚徹, 山梨裕司, 鈴木辰吾, 鈴木辰吾]
通讯作者: 鈴木辰吾
Generation of TrkA/TrkB Chimeric Receptor Constructs Reveals Molecular Mechanisms underlying BDNF-Induced Dendritic Outgrowth in Hippocampal Neurons
TrkA/TrkB 嵌合受体构建体的生成揭示了 BDNF 诱导海马神经元树突生长的分子机制
DOI: --
发表时间: 2011
期刊: CELL.MOL.NEUROBIOL
影响因子: --
作者: [Yosuke Sato, Shingo Suzuki, Mako Kitabatake,,Tomoko Hara, and Masami Kojima]
通讯作者: and Masami Kojima
8
    Construction of a Comprehensive Database of the Series of Rhyme Dictionaries "Qieyun".
    • 批准号:
      16K02671
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2016
    • 负责人:
      SUZUKI Shingo
    • 依托单位:
    Constructing Databases for the Study of the Lost-texts of the Rime Dictionary "Qieyun"
    • 批准号:
      24720178
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.66万
    • 财政年份:
      2012
    • 负责人:
      SUZUKI Shingo
    • 依托单位:
    Effect of early life stress on BDNF-mediated lipid homeostasis
    • 批准号:
      24791111
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.75万
    • 财政年份:
      2012
    • 负责人:
      SUZUKI Shingo
    • 依托单位:
    Establishment of multidrug-resistant bacteria using laboratory automation and analysis of their evolution processes
    海外基金