The search for original protein and biokinetics of antihypertensive peptide derived from Jellyfish Stomolophus nomurai

我从水母中发现了降压肽YYAPFE。该肽不具有胶原蛋白的三螺旋构象，而胶原蛋白是由[Gly-X-Y]n序列衍生的。因此，估计该肽的原蛋白为非胶原蛋白。此外，我搜索了非胶原蛋白衍生的长链肽。鉴定出一个新的非十肽，为NKPLAGSPAASELYTEAGG。然而，该肽不具有ACE抑制活性。

I found the antihypertensive peptide YYAPFE derived from Jellyfish Stomolophus nomurai. The peptide has not a characteristic triple-helical conformation of collagen that is derived from the [Gly-X-Y]n sequence. Therefore, the original protein of the peptide was estimated to be non-collagen protein. Furthermore, I searched long chain peptide derived from non-collagen protein. A new nonadecapeptide was identified as NKPLAGSPAASELYTEAGG. However, the peptide has not ACE inhivitory activity.