Effects of Partial Sleep Deprivation and Sleep Disruption on Neurobehavioral Functions

部分睡眠剥夺和睡眠中断对神经行为功能的影响

• 批准号: 22730598
• 负责人: ABE Takashi
• 金额: $ 2.66万
• 依托单位: Japan Aerospace Exploration Agency (2013)Neuropsychiatric Research Institute (2010-2012)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22730598/
• 关键词: 睡眠; 覚醒; 認知機能; ヴィジランス; 眠気; 持続的注意; 作業負荷; 徐波活動; 徐波睡眠; 覚醒水準; 部分断眠; 眼球指標

This study investigated (1) effect of sleep loss and sleep disruption on neurobehavioral functions; (2) relationship between eye metrics and deteriorated neurobehavioral performance due to sleep loss; (3) relationship between slow wave activity and daytime neurobehavioral functions during sleep restriction. This study showed that (1) one night of sleep restriction and consecutive five nights of sleep restriction cause deteriorated performance of sustained attention (vigilance); (2) PERCLOS (percent of eyelid closure time) has highest sensitivity and specificity to detect deteriorated vigilance due to sleep loss among several eye metrics; (3) slow wave suppression does not affect daytime vigilance and subjective sleepiness, but it suppresses error-monitoring function; and when combined with sleep restriction, high cognitive workload increases local (occipital) sleep homeostasis by increasing slow wave activity, suggesting a use-dependent sleep response to visual work.

本研究探讨了（1）睡眠缺失和睡眠中断对神经行为功能的影响;（2）眼指标与睡眠缺失所致神经行为功能恶化的关系;（3）睡眠限制期间慢波活动与日间神经行为功能的关系。本研究表明：（1）一晚睡眠限制和连续五晚睡眠限制会导致持续注意力的下降（2）《海洋法公约》（眼睑闭合时间的百分比）在几个眼睛度量中具有检测由于睡眠丧失而导致的警觉性恶化的最高灵敏度和特异性;（3）慢波抑制不影响白天的警觉性和主观嗜睡，但抑制错误监测功能;当与睡眠限制相结合时，高认知工作负荷通过增加慢波活动来增加局部（枕叶）睡眠稳态，这表明对视觉工作的使用依赖性睡眠反应。

项目成果

夜間睡眠の質の低下がエラー反応後の認知的処理に与える影響.

夜间睡眠质量下降对错误反应后认知处理的影响。

• 发表时间: 2011
• 作者: 浅岡章一;阿部高志;有竹清夏;笹井妙子;駒田陽子;井上雄一
• 通讯作者: 井上雄一

Effect of post-learning sleep versus wakefulness on advantageous decision-making : A preliminary study

学习后睡眠与清醒对有利决策的影响：初步研究

• DOI: 10.1111/j.1479-8425.2011.00509.x
• 发表时间: 2011
• 期刊: Sleep and Biological Rhythms
• 影响因子: 1.1
• 作者: Abe;T.;Inoue;Y.;Komada;Y.;Hori;T.
• 通讯作者: T.

Effect of Cognitive Workload on Polysomnographic Measures under Sleep Restricted and Non-Sleep Restricted Conditions

睡眠限制和非睡眠限制条件下认知工作负荷对多导睡眠图测量的影响

• 发表时间: 2012
• 作者: Abe;T .;Goel;N.;Braun;M.E.;Dinges D.F
• 通讯作者: Dinges D.F

Sleep Risks in Space : Effect of Cognitive Workload on Sleep Measures Under Sleep Restricted and Non-Sleep Restricted Conditions

太空中的睡眠风险：睡眠受限和非睡眠受限条件下认知工作负荷对睡眠测量的影响

• 发表时间: 2012
• 作者: Abe,T .;Goel,N.;Braun,M.E.;Dinges;D. F
• 通讯作者: D. F

Sleep Restriction. In: Atlas of Clinical Sleep Medicine, Second Edition (Eds.) Kryger, MH., Avidan, A. Y., & Berry, RB.

睡眠限制。

• 发表时间: 2013
• 作者: Spaeth;AM.;Abe;T.;Schneiderman;JS.;& Dinges;DF.
• 通讯作者: DF.