Mechanisms of M phase progression and cytokinesis of plant cells: a relationship to asymmetric cell division

1. 我们在烟草和拟南芥中分别鉴定出了蛋白磷酸酶的NA2C和AtNA2C基因，它们可能参与了细胞分裂所需的NACK-PQR通路的激活。我们最近的研究结果表明，AtNA2C与分生组织细胞的不对称分裂有关。2. 为了了解拟南芥gig1 - apc通路在细胞命运决定中的作用，我们寻找了可能修饰gig1表型的新突变体。我们已经确定了11种新的突变。我们的研究结果表明，GIG1和GIG1的同系物UVI4都参与了气孔的发育。3. 由于我们未能重现MAP65基因家族成员参与拟南芥根系的不对称细胞分裂，因此我们推迟了上述两种途径中基因双突变的实验。

1. We have identified NA2C and AtNA2C genes for protein phosphatases in tobacco and arabidopsis, respectively, which may be involved in activation of the NACK-PQR pathways that are required for cytokinesis. Results of our recent studies have suggested that AtNA2C is related to asymmetric cell division of meristematic cells. 2. For understanding of a role of the GIG-APC pathway of arabidopsis in cell fate determination, we have sought for new mutants that might modify gig1 phenotypes. We have identified 11 novel mutations. Results of our investigations suggest that GIG1 and UVI4, a homolg of GIG1, both are involved in development of stomata. 3. Since we failed to reproduce the involvement of members of the MAP65 gene family in asymmetric cell division in arabidopsis roots, we postponed experiments with double mutants of genes in the two pathways described above.