Elucidation of molecular mechanism of rice blast resistance

稻瘟病是水稻最重要的病害之一。稻瘟病通常由农药和抗性品种控制，但对水稻抗稻瘟病分子机制的了解有限。本研究旨在通过分析稻瘟病抗性基因Pia和稻瘟病毒力基因AVR-Pia的互作关系，阐明水稻抗稻瘟病的分子机制。本研究结果表明，AVR-Pia基因在进入水稻细胞之前就开始表达，分泌后形成同源二聚体，并被水稻Pia基因产物检测到。本研究将有助于进一步了解水稻与稻瘟病的相互作用，这是抗性诱导的第一步。

Rice blast is the most important disease or rice. Blast is usually controlled by agrochemicals and resistant cultivars, but knowledge about molecular mechanisms of rice resistance toward blast is limited. This study aimed to elucidate the molecular mechanism of rice blast resistance by analyzing interaction of rice blast resistance gene Pia and blast virulence gene AVR-Pia. Results of this study indicated that AVR-Pia gene is started to be expressed before the penetration into rice cells, and after the secretion, AVR-Pia protein forms homodimer, and detected by rice Pia gene product. This study will contribute to further understanding of rice-rice blast interaction, which is the first step of resistance induction.