The genomic epidemiology and immunological cohort study on amoebiasis in South Asia
The genomic epidemiology and immunological cohort study on amoebiasis in South Asia
批准号:
23406009
负责人:
HAMANO Shinjiro
金额:
$12.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-01 至 2014-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In Mirpur, Dhaka, Bangladesh, natural exposure to Entamoeba spp. in infancy was prospectively observed. Approxymately, 80% of children had been infected with Entamoeba histolytica by age two years, with around 20% having suffered from E. histolytica. Furthermore, newly acquired E. moshkovskii infection was associated with diarrhea. Genetic analysis revealed that E. moshkovskii isolates infecting children were genetically heterogeneous, as evidenced by PCR typing of tRNA locus R-R. It will be important in future studies of the potential pathogenicity of E. moshkovskii to take into account this heterogeneity, as for the case of E. histolytica, not every genotype is equally capable of causing disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Entamoeba moshkovskii is pathogenic and causes intestinal symptoms.
莫什科夫斯基内阿米巴具有致病性,会引起肠道症状。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Chikako Shimokawa, Mamum Kabir, Mami Taniuchi, Dinesh Mondal, Seiki Kobayashi, Ibne Karim M. Ali, Masachika Senba, Eric Hoput, Haque Rashidul, William A. Petri Jr., Shinjiro Hamano:]
通讯作者:
Shinjiro Hamano:
Intestinal inflammatory mediated clearance of Entamoeba moshkovskii isdependent on IFN-γ
莫什科夫斯基内阿米巴肠道炎症介导的清除依赖于 IFN-γ
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Gaowa, Yoshikawa, Y., Ohashi, N., Wu, D., Kawamori, F., Ikegaya, A., Watanabe, T., Saitoh, K., Takechi, D., Murakami, Y., Shichi, D., Aso, K., and Ando, S., Shinjiro Hamano and Chikako Shimokawa]
通讯作者:
Shinjiro Hamano and Chikako Shimokawa
Intestinal inflammatory mediated clearance of Entamoeba moshkovskii is dependent on IFN-γ. Forum Cheju 16
莫什科夫斯基内阿米巴的肠道炎症介导的清除依赖于 IFN-γ Forum Cheju 16。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Takano, I., Fujita, H., Kadosaka, T., Takahashi, M., Yamauchi, T. Ishiguro, F., Takada, N., Yano, Y., Oikawa, Y., Honda, T., Gokuden, M., Tsunoda, T., Tsurumi, M., Ando, S., Andoh, M., Sato, K., Kawabata, H., Shinjiro Hamano and Chikako Shimokawa]
通讯作者:
Shinjiro Hamano and Chikako Shimokawa
IFN-・ is necessary for clearance of pathogenic amoebae from the intestine of mice
IFN-·对于清除小鼠肠道中的致病性阿米巴原虫是必需的
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Chikako Shimokawa, Shinjiro Hamano]
通讯作者:
Shinjiro Hamano
アメーバ症, 今日の診断指針第7版
阿米巴病,今日诊断指南第七版
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Gaowa, Wuritu, Wu D, Yoshikawa Y, Ohashi N, Kawamori1 F, Sugiyama K, Ohtake M, Ohashi M, Yamamoto S, Kitano T, Takada N, and Kawabata H, Shinjiro Hamano and Chikako Shimokawa, 濱野真二郎]
通讯作者:
濱野真二郎
共 26 条
Immunological cohort study on amebiasis in South Asia
-
批准号:26305013
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.4万
-
财政年份:2014
-
负责人:HAMANO Shinjiro
-
依托单位:
Elucidation of pathological process of schistosomiasis using multiphoton fluorescence microscopy and PET/SPECT
-
批准号:25670204
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2013
-
负责人:HAMANO Shinjiro
-
依托单位:
Analyses and Evaluation of the effects of environmental factors on the outcome of leishmaniasis
-
批准号:21590465
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2009
-
负责人:HAMANO Shinjiro
-
依托单位:
The genomic epidemiology and immunological cohort study on amoebiasis in South Asia
-
批准号:20406008
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.82万
-
财政年份:2008
-
负责人:HAMANO Shinjiro
-
依托单位:
DNA vaccine targeting both liver and blood stage of virulent strain Plasmodium
-
批准号:19590429
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2007
-
负责人:HAMANO Shinjiro
-
依托单位:
海外基金