Relationship between breast milk dioxin concentrations and steroid hormone levels in Vietnamese

越南人母乳二恶英浓度与类固醇激素水平的关系

• 批准号: 23590735
• 负责人: OKAMOTO Rie
• 金额: $ 3.49万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23590735/
• 关键词: 環境保健; ダイオキシン; 健康被害

The purpose of this study was to clarify the association of dioxin in breast milk and steroid hormone in serum and saliva, primiparae's growth by comparing the defoliant sprayed area and non-sprayed area in Vietnam. The subjects were mother aged between 20 and 30 years old and their primiparae aged between 4 and 16 weeks, each 50 pairs.Almost Dioxin isomer concentrations from sprayed area were higher than non-sprayed area. Dioxin concentrations showed U-shaped relationship with some steroid hormone levels. Girl's growth showed stronger relationship with dioxin concentrations and steroid hormone levels than boy's growth.

本研究的目的是通过对越南落叶剂喷洒地区和非喷洒地区的比较，阐明母乳中的二恶英与血清和唾液中的类固醇激素以及初产妇生长发育之间的关系。研究对象为20~30岁的母亲和4~16周龄的初产妇，每对50对。喷洒地区的二恶英异构体浓度几乎都高于非喷洒地区。二恶英浓度与某些类固醇激素水平呈U型关系。女孩的生长发育与二恶英浓度和类固醇激素水平的关系要强于男孩的生长发育。