Head-out immersion in hot water increases serum levels of IL-6.

将头浸入热水中会增加血清中 IL-6 的水平。

• 批准号: 23590894
• 负责人: TAJIMA Fumihiro
• 金额: $ 2.91万
• 依托单位: Wakayama Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23590894/
• 关键词: 頚下浸水; 温泉浴; 中枢温; 運動療法; 温熱療法; インターロイキン－６; ＴＮＦ－α; サイトカイン; ＴＮＦα; インターロイキン６; TNFα

We hypothesized that head-out hot water immersion (heat stress) increases serum IL-6 in human. Each of 8 healthy adults performed 6 different tests of 30-min rest/20-min intervention/60-min recovery, including rest in air (RA, room temperature 28C), rest during thermoneutral (35.5C) water immersion (RIN), rest during hot (42.0C) water immersion (RIH), exercise in air (EA, ergometer exercise at 60% of VO2max), exercise during thermoneutral water immersion (EIN), and exercise during hot water immersion (EIH). RIH and EIH increased core temperature during and after the immersion and serum levels of IL-6 at recovery period, and the increase in IL-6 level was greater than in RA and RIN. Exercise did not significantly increase IL-6 in EA and EIN. EIH markedly increased IL-6, although the magnitude of the increase was not significantly higher than RIH. These findings demonstrated that hot water immersion increases serum IL-6 through increased body core temperature.

我们假设头部热水浸泡（热应激）会增加人血清IL-6。8名健康成人分别进行了6项不同的30分钟休息/20分钟干预/60分钟恢复试验，包括空气休息（RA，室温28℃）、热中性（35.5℃）水浸泡（RIN）休息、热浸泡（42.0℃）水浸泡（RIH）休息、空气运动（EA， 60%最大摄氧量的测力仪运动）、热中性水浸泡（EIN）运动和热水浸泡（EIH）运动。RIH和EIH组浸泡期间和浸泡后核心温度升高，恢复期血清IL-6水平升高，且IL-6水平升高幅度大于RA和RIN组。运动未显著增加EA和EIN的IL-6。EIH显著增加IL-6，但升高幅度不明显高于RIH。这些结果表明，热水浸泡通过提高体温升高血清IL-6。

项目成果

温泉入浴における血中IL-6動態

泡温泉时血IL-6动态

• 发表时间: 2011
• 作者: 梅本安則;下松智哉;児嶋大介;木下利喜生;中村健;田島文博
• 通讯作者: 田島文博

温水頚下浸水前後における血中BDNF濃度の変化

温水宫颈下浸泡前后血液BDNF浓度变化

• 发表时间: 2012
• 作者: 佐々木裕介;梅本安則;田島文博
• 通讯作者: 田島文博

ゴルフラウンド前後の血中ＩＬ－６動態

高尔夫球赛前后的血液 IL-6 动态

• 发表时间: 2012
• 作者: 梅本安則;安岡良訓;尾川貴洋;佐々木裕介;幸田剣;田島文博
• 通讯作者: 田島文博

温熱負荷時の血中IL-6・BDNF動態

热负荷期间的血液 IL-6/BDNF 动态

• 发表时间: 2013
• 作者: 梅本安則;幸田剣;橋﨑孝賢;森木貴司;寺村健三;田島文博
• 通讯作者: 田島文博

Cardiovascular responses to arm static exercise in men with thoracic spinal cord lesions

胸脊髓病变男性对手臂静态运动的心血管反应

• DOI: 10.1007/s00421-011-2017-x
• 发表时间: 2012
• 期刊: European Journal of Applied Physiology
• 影响因子: 3
• 作者: Keiko Sakamoto;Takeshi Nakamura;Y. Umemoto;Yumi Koike;Y. Sasaki;F. Tajima
• 通讯作者: F. Tajima