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The pathophysiology of EB virus infection, and screening investigational drugs using a new human tissue model

The pathophysiology of EB virus infection, and screening investigational drugs using a new human tissue model
EB 病毒感染的病理生理学,以及利用新的人体组织模型筛选研究药物
批准号:
23591564
负责人:
ITO Yoshinori
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

项目摘要

项目成果

ITO Yoshinori的其他基金

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中文摘要
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英文摘要
Epstein-Barr virus (EBV) causes intractable diseases, including EBV-associated malignancies. Using a new human tissue model, EBV-infected cells were analyzed during the early stage of infection. Naive and memory B cells were found to be infected with EBV. The potential effects of the investigational drugs bortezomib, rapamycin, and mogamulizumab were analyzed using the human tissue model and a murine xenograft model. They showed therapeutic effects in the models.
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会议论文
Hyperferritinemia in Neonatal and Infantile Human Parechovirus-3 Infection in Comparison with Other Infectious Diseases.
与其他传染病相比,新生儿和婴儿人副肠病毒-3 感染中的高铁蛋白血症。
DOI: 10.1016/j.jiac.2013.11.002
发表时间: 2014
期刊: Journal of Infection and Chemotherapy
影响因子: 2.2
作者: [Hara S, Kawada J, Kawano Y, Yamashita T, Minagawa H, Okumura N, Ito Y.]
通讯作者: Ito Y.
Immunogenicity of inactivated 2009 H1N1 influenza vaccine in pediatric liver transplant recipients
2009 H1N1 流感灭活疫苗对儿童肝移植受者的免疫原性
DOI: 10.1016/j.vaccine.2011.04.012
发表时间: 2011
期刊: Vaccine
影响因子: 5.5
作者: [Torii, Y. Kimura, H. Ochi, N. Kaneko, K. Ando, H. Kiuchi, T. Ito, Y.]
通讯作者: Y.
Late-onset sensorineural hearing loss due to asymptomatic congenital cytomegalovirus infection retrospectively diagnosed by polymerase chain reaction using preserved umbilical cord.
使用保存的脐带通过聚合酶链反应回顾性诊断无症状先天性巨细胞病毒感染导致的迟发性感音神经性听力损失。
DOI: 10.1177/0009922810380903
发表时间: 2011
期刊: Clin Pediatr
影响因子: 1.6
作者: [Ikeno M, et al.]
通讯作者: et al.
DOI: 10.1111/ped.12122
发表时间: 2013-10-01
期刊: PEDIATRICS INTERNATIONAL
影响因子: 1.4
作者: [Ito, Yoshinori, Kimura, Hiroshi, Moriuchi, Hiroyuki]
通讯作者: Moriuchi, Hiroyuki
54
    Next-generation sequencing
    Development and Dissemination of Compassion-Based Educational Program for Bullying Prevention
    • 批准号:
      26380932
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2014
    • 负责人:
      ITO Yoshinori
    • 依托单位:
    Creation and efficacy of the new type of cognitive behavioral intervention program that was constructed by non-meditative element
    • 批准号:
      22530746
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.75万
    • 财政年份:
      2010
    • 负责人:
      ITO Yoshinori
    • 依托单位:
    Environmental Taxes and the Polluter Pays Principle
    • 批准号:
      21730022
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $0.75万
    • 财政年份:
      2009
    • 负责人:
      ITO Yoshinori
    • 依托单位: