Fundamental and clinical evaluation for the optimization of diagnostic imaging of the temporal bone using 3T MRI

使用 3T MRI 优化颞骨诊断成像的基础和临床评估

• 批准号: 23591783
• 负责人: KODAMA Takao
• 金额: $ 3.16万
• 依托单位: University of Miyazaki
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23591783/
• 关键词: 核磁気共鳴画像（MRI); 高磁場装置; ３T; 拡散強調画像; 高分解能画像; 側頭骨; 真珠腫; 3T MRI; 磁気共鳴画像（MRI）; 3T; 角磁気共鳴画像（MRI）

The purpose of this research is to decide appropriate protocols of high-resolution MR imaging for the temporal bone pathologies at 3T, especially about 3D high-resolution imaging and diffusion-weighted imaging (DWI).For 3D high-resolution imaging, a fast spin echo sequence was better than a gradient echo sequence because of its less vulnerability to susceptibility effects.We obtained following results about DWI. 1) A single shot EPI (echo-planar imaging) sequence was not suitable because of its vulnerability to susceptibility. 2) ADC (apparent diffusion coefficient) value could enhance the diagnostic capability of DWI for a cholesteatoma. 3) DWI using 3D PSIF, one of non-EPI sequences, could be a robust sequence for temporal bone pathologies because of its high spatial resolution and less susceptibility artifacts. 4) DWI using readout-segmented EPI provided higher image quality and lesion conspicuity than single shot EPI. However, this technique had some problems to be resolved.

本研究的目的是确定适合颞骨病变的3T高分辨MR成像方案，特别是3D高分辨成像和扩散加权成像（DWI），对于3D高分辨成像，快速自旋回波序列比梯度回波序列更容易受到磁敏感效应的影响，我们得到以下结果：1)单次激发EPI（回波平面成像）序列是不合适的，因为它的易感性。2)表观扩散系数（ADC）值可提高扩散加权成像对中耳乳突瘤的诊断能力。3)非EPI序列之一的3D PSIF DWI具有空间分辨率高、磁敏感伪影少等优点，可作为颞骨病变的一种可靠序列。4)DWI使用读出分段EPI提供了更高的图像质量和病变的显着性比单次激发EPI。不过，这种技术也存在一些问题。