Study on new sperm laboratory procedure for appropriate treatment options in the assisted reproductive technology

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Half of infertile couples are caused by a male factor. However, the most of the cause are unknown. Therefore, it is forced to use current state assisted reproductive technology (ART). Research delegates worked on the development of new tests that can diagnose the fertility of sperm for the treatment decision-in addition to a conventional semen analysis (sperm concentration, motility and morphology). Semenogelin (Sg), seminal vesicle protein is one of the causes of asthenozoospermia.Therefore, Sg binding rate and the amount of binding to the sperm of male infertility patients and partners of fertile women as control were measured. As a result, it was revealed that these parameters were significantly higher in former cases than in latter. In the future, it is necessary to clarify association with the relevance pregnancy rate and the birth rate of infertile couple whether the measurements of Sg binding to male infertile patient's sperm can be a new method for semen analysis.