Analysis of the roles of Galectins during placentation
Analysis of the roles of Galectins during placentation
批准号:
23592423
负责人:
SHOJI Hiroki
金额:
$3.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
Galectins comprise a family of animal lectin that bind to beta-galactoside-containing carbohydrates. In this study, we aimed to clarify the roles of galectins during placentation. Analysis of functions of galectins during the differentiation process of rat trophoblast cell line (Rcho-1 cell) revealed that down regulation of Galectin 4 expression may be involved in the promotion of trophoblast cell differentiation. The findings of current study contribute to the understanding of the regulatory mechanisms of placentation by members of galectin family.
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ガレクチンによる制御を介した胎盤形成・維持機構の解析
半乳糖凝集素控制介导的胎盘形成和维持机制分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[有川智博, 島村英理子, 島田ひろき, 八田稔久, 東海林博樹]
通讯作者:
東海林博樹
Leukemia inhibitory factor induces expression of insulin-like growth factor 1 and 2 in the forebrain of rat fetuses via maternal-fetal leukemia inhibitory factor signal pathway
白血病抑制因子通过母胎白血病抑制因子信号通路诱导大鼠胎儿前脑胰岛素样生长因子1和2的表达
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[T.Hatta, H.Shimada, E.Simamura, H.Shoji, N.Higashi]
通讯作者:
N.Higashi
Analysis of the Galectin 4 expression during trophoblast differentiation in rat placentation
大鼠胎盘滋养层分化过程中半乳糖凝集素4的表达分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Arikawa T, Simamura E, Shimada H, Hatta T, Shoji H]
通讯作者:
Shoji H
T cells control innate hyperinflammation in LPS endotoxemia by downregulating macrophage TNF production via IRAK-1-mediated IL-10 expression
T 细胞通过 IRAK-1 介导的 IL-10 表达下调巨噬细胞 TNF 的产生来控制 LPS 内毒素血症中的先天性过度炎症
DOI:
--
发表时间:
2014
期刊:
Proceedings of National Academy of Sciences of the United States of America
影响因子:
--
作者:
[Inoue M, Arikawa T, Chen YH, Moriwaki Y, Price M, Brown M, Perfect JR, Shinohara ML]
通讯作者:
Shinohara ML
DOI:
10.1111/j.1741-4520.2011.00316.x
发表时间:
2011-06
期刊:
Congenital Anomalies
影响因子:
1.3
作者:
[E. Simamura;H. Shimada;H. Shoji;H. Otani;T. Hatta]
通讯作者:
E. Simamura;H. Shimada;H. Shoji;H. Otani;T. Hatta
共 23 条
Roles of galectins during trophoblast differentiation into invasive cells
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批准号:17K11258
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2017
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负责人:SHOJI Hiroki
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依托单位:
Regulation of acquirement of invasiveness in placental trophoblasts by galectin family
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批准号:26462502
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2014
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负责人:SHOJI Hiroki
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依托单位:
海外基金