The development of 3D cartilage regeneration therapy using the human auricular cartilage progenitor cells with autologous serum.

我们已经成功地分离出人软骨祖细胞（hCPCs）并从它们中再生软骨。从耳廓软骨膜中分离的hCPCs不仅具有人软骨细胞（hCs）所不具有的高增殖能力和多能性，而且具有与hCs相同的软骨细胞外基质能力，我们的目的是在hCPCs培养技术的基础上，发展可用于临床的hCPCs的操作技术。 具体而言，有（1）hCPC表征的实施（2）体内再生软骨的评价（3）源自hCPC的3D软骨再生的开发（4）自体血清技术的开发。

We have succeeded in isolating Human cartilage progenitor cells (hCPCs) and regenerating cartilage derived from them. The hCPCs which were isolated from auricular perichondrium had not only high proliferative and multipotent capacity that human chondrocytes (hCs) did not have, but had same cartilage extracellular matrix capacity as hCs.Our purpose is to develop handing skill that could apply hCPCs in clinical setting on the basis of their culture technique. Specifically, there are (1) Implementation of hCPCs characterization (2) Evaluation of regenerated cartilage in vivo (3) The development of 3D cartilage regeneration derived from hCPCs (4) The development of autologous serum technique.