Establishment of the assessment method of salivery function by perfusion/diffusion MR imaging without using contrast agent.

不使用造影剂的灌注/扩散磁共振成像评估唾液功能方法的建立

• 批准号: 23592772
• 负责人: SASAKI Miho
• 金额: $ 3.41万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592772/
• 关键词: MRI; 灌流; 拡散; 唾液腺機能; ＭＲＩ; ＩＶＩＭ; MRＩ; 拡散強調撮像

The aim of this study is to establish the new evaluation technique for the assessment of salivary gland perfusion and diffusion function using diffusion weighted MR imaging. Various diffusion weighted MR imaging parameters were tested, such as b-values, TRs and TEs, number of acquisition. We could achieve the imaging time within 10sec, which was enough to evaluating the salivary function before and after gustatory stimulation. We also established the head fixing gear and gustatory stimulation appliance. Healthy volunteer study revealed the good performance of this newly established method.

本研究旨在建立一种新的磁共振弥散加权成像评价涎腺灌注和弥散功能的方法。测试了各种扩散加权MR成像参数，如b值、TR和TE、采集次数。成像时间在10秒以内，足以评价味觉刺激前后唾液腺功能的变化。建立了头部固定装置和味觉刺激器。健康志愿者的研究显示了这种新建立的方法的良好性能。

项目成果

Intravoxel incoherent motion imaging of masticatory muscles : A pilot study for the assessment of perfusion and diffusion during clenching

咀嚼肌的体素内不相干运动成像：评估咬紧过程中灌注和扩散的初步研究

• 发表时间: 2013
• 期刊: AJR Am J Roentogenol
• 作者: Sasaki M;Sumi M;Nakamura T
• 通讯作者: Nakamura T

In Vitro Measurement Of Apoptotic And Non-apopttic Cells Using Diffusion- Weighted MR

使用扩散加权 MR 体外测量凋亡和非凋亡细胞

• 发表时间: 2013
• 作者: Yuka hotokezaka;Sato Eida;Ikuo Katayama;Miho Sasaki;Misa Sumi;Takashi Nakamura
• 通讯作者: Takashi Nakamura

Head and Neck Tumors: Assessment of Perfusion-Related Parameters and Diffusion Coefficients Based on the Intravoxel Incoherent Motion Model

• DOI: 10.3174/ajnr.a3227
• 发表时间: 2013-02-01
• 期刊: AMERICAN JOURNAL OF NEURORADIOLOGY
• 影响因子: 3.5
• 作者: Sumi, M.;Nakamura, T.
• 通讯作者: Nakamura, T.

Head and neck tumours: combined MRI assessment based on IVIM and TIC analyses for the differentiation of tumors of different histological types

• DOI: 10.1007/s00330-013-3002-z
• 发表时间: 2014-01-01
• 期刊: EUROPEAN RADIOLOGY
• 影响因子: 5.9
• 作者: Sumi, Misa;Nakamura, Takashi
• 通讯作者: Nakamura, Takashi

Extranodal Spread in the Neck: MRI Detection on the Basis of Pixel-Based Time-Signal Intensity Curve Analysis

• DOI: 10.1002/jmri.22454
• 发表时间: 2011-04-01
• 期刊: JOURNAL OF MAGNETIC RESONANCE IMAGING
• 影响因子: 4.4
• 作者: Sumi, Misa;Nakamura, Takashi
• 通讯作者: Nakamura, Takashi