Establishment of the assessment method of salivery function by perfusion/diffusion MR imaging without using contrast agent.

不使用造影剂的灌注/扩散磁共振成像评估唾液功能方法的建立

• 批准号: 23592772
• 负责人: SASAKI Miho
• 金额: $ 3.41万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592772/
• 关键词: MRI; 灌流; 拡散; 唾液腺機能; ＭＲＩ; ＩＶＩＭ; MRＩ; 拡散強調撮像

The aim of this study is to establish the new evaluation technique for the assessment of salivary gland perfusion and diffusion function using diffusion weighted MR imaging. Various diffusion weighted MR imaging parameters were tested, such as b-values, TRs and TEs, number of acquisition. We could achieve the imaging time within 10sec, which was enough to evaluating the salivary function before and after gustatory stimulation. We also established the head fixing gear and gustatory stimulation appliance. Healthy volunteer study revealed the good performance of this newly established method.

这项研究的目的是建立新的评估技术，用于使用扩散加权MR成像评估唾液腺灌注和扩散功能。测试了各种扩散加权的MR成像参数，例如B值，TRS和TES，收购数量。我们可以在10秒内达到成像时间，这足以评估味觉刺激前后的唾液功能。我们还建立了头固定齿轮和味觉刺激设备。健康的志愿者研究揭示了这种新建立的方法的良好表现。

项目成果

Intravoxel incoherent motion (IVIM) MRIの唾液腺腫瘍への応用

体素内不相干运动（IVIM）MRI在唾液腺肿瘤中的应用

• 发表时间: 2011
• 作者: 角美佐;佐々木美穂;角忠輝;木村泰男;高木幸則;榮田智;市川陽子;中村卓
• 通讯作者: 中村卓

Intravoxel incoherent motion imaging of masticatory muscles : A pilot study for the assessment of perfusion and diffusion during clenching

咀嚼肌的体素内不相干运动成像：评估咬紧过程中灌注和扩散的初步研究

• 发表时间: 2013
• 期刊: AJR Am J Roentogenol
• 作者: Sasaki M;Sumi M;Nakamura T
• 通讯作者: Nakamura T

In Vitro Measurement Of Apoptotic And Non-apopttic Cells Using Diffusion- Weighted MR

使用扩散加权 MR 体外测量凋亡和非凋亡细胞

• 发表时间: 2013
• 作者: Yuka hotokezaka;Sato Eida;Ikuo Katayama;Miho Sasaki;Misa Sumi;Takashi Nakamura
• 通讯作者: Takashi Nakamura

Comparison between ultrasonography and MR imaging for discriminating squamous cell carcinoma nodes with extranodal spread in the neck

• DOI: 10.1016/j.ejrad.2012.06.018
• 发表时间: 2012-11-01
• 期刊: EUROPEAN JOURNAL OF RADIOLOGY
• 影响因子: 3.3
• 作者: Katayama, Ikuo;Sasaki, Miho;Nakamura, Takashi
• 通讯作者: Nakamura, Takashi

IgG4-related Mikulicz's disease : Ultrasonography of the salivary and lacrimal glands for monitoring the efficacy of corticoid therapy

IgG4 相关的米库利茨病：唾液腺和泪腺超声检查以监测皮质激素治疗的疗效

• 发表时间: 2013
• 期刊: Clin Exp Rheumatol
• 影响因子: 3.7
• 作者: Takagi Y;Nakamura H;Origuchi T;Miyashita T;Kawakami A;Sumi M;Nakamura T
• 通讯作者: Nakamura T