Establishment of the assessment method of salivery function by perfusion/diffusion MR imaging without using contrast agent.

本研究旨在建立一种新的磁共振弥散加权成像评价涎腺灌注和弥散功能的方法。测试了各种扩散加权MR成像参数，如b值、TR和TE、采集次数。成像时间在10秒以内，足以评价味觉刺激前后唾液腺功能的变化。建立了头部固定装置和味觉刺激器。健康志愿者的研究显示了这种新建立的方法的良好性能。

The aim of this study is to establish the new evaluation technique for the assessment of salivary gland perfusion and diffusion function using diffusion weighted MR imaging. Various diffusion weighted MR imaging parameters were tested, such as b-values, TRs and TEs, number of acquisition. We could achieve the imaging time within 10sec, which was enough to evaluating the salivary function before and after gustatory stimulation. We also established the head fixing gear and gustatory stimulation appliance. Healthy volunteer study revealed the good performance of this newly established method.