The effect of the sensitivity in the esophagus mucous on a parafunction of the stomatognathic system

为了阐明软腭味蕾化学感受的机制，我们研究了味觉感受器gustducin的共表达以及对几种甜味和苦味化合物的神经反应。我们的研究结果表明，甜和苦的信号转导存在区域差异和香料差异。此外，我们还比较了错颌患者和正常人的口腔形态和咀嚼功能，以揭示胃肠道疾病与口颌功能异常的关系。我们的研究结果表明，咬合力与正常受试者的咀嚼颌部运动和咀嚼性能密切相关，单侧后剪型咬合错患者可能表现出独特的咀嚼模式和肌肉活动。

To clarify the mechanism of chemoreception in soft palate taste buds, we examined the co-expression of gustducin with taste receptors and the neural responses to several sweet and bitter compounds. Our results suggest that the regional and spices differences exist in both sweet and bitter signal transduction. Furthermore, we evaluate the morphology and the masticatory function in patients with malocclusion and normal subjects to reveal the relationship between the gastrointestinal disease and stomatognathic parafunction. Our findings suggest that the bite force is closely related to the masticatory jaw movements and masticatory performance in normal subject, and the patients with unilateral posterior scissors-bite malocclusion may behave the unique masticatory chewing pattern and muscle activity.