Influence of eating patterns on energy metabolism and visceral fat deposition in rats

一般来说，狼吞虎咽的饮食模式被认为是增加内脏脂肪沉积相比，蚕食模式的饮食。然而，从来没有足够的科学证据。在本研究中，我们比较了进食频率，一天一次（狼吞虎咽组）和一天三次（啃食组），对能量代谢，内脏脂肪沉积和肝脏脂质代谢的影响高脂肪饮食大鼠。与啃食组相比，狼吞虎咽组的呼吸商（RQ）较高，脂肪消耗量较低。两组的总能量消耗相同。各组的最终体重和内脏脂肪重量几乎相同。但不同的进食频率会影响血糖、血清胰岛素、血清脂联素和肝脏三酰甘油的浓度。这些观察结果表明，内脏脂肪沉积不受进餐频率的影响，至少在这个实验条件下，但碳水化合物和脂质代谢的饮食习惯改变。

Generally, gorging pattern of eating has been thought to increase visceral fat deposition compared to nibbling pattern of eating. However, sufficient scientific proof has never been available. In the present study, we compared effects of meal frequency, once a day(gorging group) and thrice a day (nibbling group), on energy metabolism, visceral fat deposition and hepatic lipid metabolism in rats fed a high fat diet. Respiratory quotient (RQ) was higher and fat consumption was lower in the gorging group compared with the nibbling group. Total energy consumption was the same between the two groups. Final body weight and visceral fat weight were almost the same between the groups. However, concentrations of blood glucose, serum insulin, serum adiponectin and hepatic triacylglycerol were influenced by different meal frequency. These observations suggest that visceral fat deposition is not influenced by meal frequency at least in this experimental condition, but carbohydrate and lipid metabolisms are altered by eating habits.