Demonstration of the formation of cyclobutane pyrimidine dimers through the excited triplet state mediated by solar UV radiation

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I tried to demonstrate that the formation of cyclobutane pyrimidine dimers (CPDs) by long wavelength UV radiations is mediated by a photochemical reaction through the excited triplet states of DNA bases. However, it was reported by others that the long wavelength UV-induced CPD formation is mediated by another novel mechanism, which made us change the goal of this research and characterize the novel mechanism by studying comparatively the mutation spectra induced by long wavelength UV. We found that solar-UV signature mutations, which we had identified before as solar UV-specific mutations, are caused through the CPDs produced by this novel mechanism, and are induced most efficiently by UVA1.