Functionalization of crystalline channels with multiple recognition sites

具有多个识别位点的晶体通道的功能化

• 批准号: 23655117
• 负责人: SHIONOYA Mitsuhiko
• 金额: $ 2.5万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23655117/
• 关键词: 多孔性結晶; 自己集合; 超分子; 大環状金属錯体; ホスト・ゲスト化学; X線構造解析; 分子認識; 機能性結晶; 超分子金属錯体; 不斉結晶化

It was found in this study that trinuclear Pd complexes of a macrocyclic N6-type ligand simultaneously form four kinds of conformational and stereo isomers in solution and that self-assembly of these isomers results in crystalline nanochannel structure of ca. 2 nm diameter. In the channel, five enantio-paired pockets and various types of hydrogen bonding sites are arranged. In the guest adsorption experiments, a single-crystal was soaked in a guest solution for a given time, and then the position and adsorption patterns of the guest was determined by single-crystal X-ray structural analysis. This method has revealed the adsorption positions of many types of aromatic compounds, metal catalysts, and bio-related compounds, which allowed adsorption mapping. Moreover, simultaneous site-selective adsorption of different multiple guests has been achieved and further developed to multicomponent intermolecular reactions in the channel.

本研究发现，大环n6型配体的三核钯配合物在溶液中同时形成四种构象和立体异构体，这些异构体的自组装形成直径约为2 nm的纳米通道晶体结构。通道中有5个对映体配对的口袋和各种类型的氢键位点。在客体吸附实验中，将单晶在客体溶液中浸泡一定时间，然后通过单晶x射线结构分析确定客体的位置和吸附模式。该方法揭示了多种芳香族化合物、金属催化剂和生物相关化合物的吸附位置，从而实现了吸附作图。此外，还实现了不同多客体的同时选择性吸附，并进一步发展为通道内的多组分分子间反应。

项目成果

Metal-templated Supramolecular Desing : Functional Array, Space, and Motion, Challenges in Organic Materials and Supramolecular Chemistry

金属模板超分子设计：功能阵列、空间和运动、有机材料和超分子化学的挑战

• 发表时间: 2013
• 作者: 田代省平;高松紀仁;大坪主弥;北川宏;塩谷光彦;大原裕樹・森本正和・深港豪・玉置信之・入江正浩;和田健彦;T. Nakamura;M. Shionoya
• 通讯作者: M. Shionoya

Metal-templated Supramolecular Design: Functional Array, Space, and Motion

金属模板超分子设计：功能阵列、空间和运动

• 发表时间: 2013
• 作者: Mitsumoto;K.; Nishikawa;H.; Oshio;H.;大内誠，澤本光男;田代省平;M. Shionoya
• 通讯作者: M. Shionoya

塩谷研究室 Bioinorganic Chemistry Laboratory

盐谷实验室生物无机化学实验室

塩谷研究室

盐谷实验室

Palladium- or Proton-induced Submicro Spherical Aggregation of Macrocyclic Amphiphiles in Aqueous Solution

水溶液中钯或质子诱导的大环两亲物的亚微米球形聚集

• DOI: 10.1039/c3dt51827b
• 发表时间: 2013
• 期刊: Dalton Transactions
• 影响因子: 4
• 作者: S. Tashiro;R. Kubota;M. Kawagoe;M. Shionoya
• 通讯作者: M. Shionoya