Functionalization of crystalline channels with multiple recognition sites

研究发现，大环N6型配体的三核钯配合物在溶液中同时形成四种构象异构体和立体异构体，这些异构体的自组装形成了ca. 2 nm直径。在通道中，五个对映体配对的口袋和各种类型的氢键位点排列。在客体吸附实验中，将单晶在客体溶液中浸泡给定时间，然后通过单晶X射线结构分析确定客体的位置和吸附模式。该方法揭示了许多类型的芳香族化合物、金属催化剂和生物相关化合物的吸附位置，从而允许进行吸附绘图。此外，不同的多个客体的同时位点选择性吸附已经实现，并进一步发展到多组分分子间反应的通道。

It was found in this study that trinuclear Pd complexes of a macrocyclic N6-type ligand simultaneously form four kinds of conformational and stereo isomers in solution and that self-assembly of these isomers results in crystalline nanochannel structure of ca. 2 nm diameter. In the channel, five enantio-paired pockets and various types of hydrogen bonding sites are arranged. In the guest adsorption experiments, a single-crystal was soaked in a guest solution for a given time, and then the position and adsorption patterns of the guest was determined by single-crystal X-ray structural analysis. This method has revealed the adsorption positions of many types of aromatic compounds, metal catalysts, and bio-related compounds, which allowed adsorption mapping. Moreover, simultaneous site-selective adsorption of different multiple guests has been achieved and further developed to multicomponent intermolecular reactions in the channel.