Develppment of Non-tocic and Luminescent Nanoparticles for Bioimaging

我们成功地合成了发光和无毒的纳米颗粒，用于精确监测生物分子相互作用事件。通过选择结构(尺寸、物相、组成)受到严格控制的纳米粒子，发射的调谐范围覆盖了300-2000 nm的NUV-VIS-NIR区域。对纳米颗粒表面的控制提供了水溶性，随后利用纳米颗粒的发光实现了体内和体外生物监测的成功，所有纳米颗粒都是无毒的。

We successfully synthesized luminescent and non-toxic nanoparticles for precise monitoring ofbiomolecular interaction events. The tuning range of emission covers over 300-2000 nm of NUV-VIS-NIR region by choosing the nanoparticles in which the structures (size, phase, composition) are carefully controlled. Control over the nanoparticle surfaces provides the water solubility, and subsequently leads to the success of in-vivo andin-vitro biomonitoring by taking advantage of luminescence from the nanoparticles.All of nanoparticles are non-toxic.