Clarificaiton of Cuase of Occurrence and Biomechanism of Pressure Ulcer by Image-based Finite Element Method

基于图像的有限元法阐明压疮发生原因及生物机制

• 批准号: 23656092
• 负责人: TAKANO NAOKI
• 金额: $ 2.5万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23656092/
• 关键词: 有限要素法; モンテカルロ法; 裾野確率; サンプリング法; 褥瘡; 看護・介護; イメージベースモデリング; 界面切欠き; ｲﾒｰｼﾞﾍﾞｰｽﾓﾃﾞﾘﾝｸﾞ; 皮膚特性; 生体力学; マルチスケール法

It is important to clarify the fundamental cause of occurence of pressur ulcer to improve the nursing care for its prevention. Based on the hypothesis that the initial cause of pressur ulcer lies in the damage of fibril tissue at the interface between bone and muscle in the human buttock, in this study, interfacial strain analysis was carried out by image-based finite element method and the biomechanism was discussed. An original computational method has been developed to find the pair of parameters that lead to high strain value in the Monte Carlo simulation considering the uncertainties in 7 parameters. They are the mechanical properties of fat and muscle, volume fraction of fat, location and size of damage and positioning. The numerical results implied that the risk of fibril tissue damage due to shear strain increased if the Young's moduli of fat and muscle are low for such patient that has high volume fraction of fat, lying on bed in supine position.

明确压疮发生的根本原因，对改善压疮预防护理具有重要意义。基于人体臀部骨肌交界面纤维组织损伤是造成压疮的最初原因的假设，本研究采用基于图像的有限元方法进行了界面应变分析，并对其生物机制进行了探讨。在蒙特卡罗模拟中，考虑到7个参数的不确定性，提出了一种新颖的计算方法来寻找导致高应变值的参数对。它们是脂肪和肌肉的力学特性，脂肪的体积分数，损伤的位置和大小以及定位。数值结果表明，对于这种脂肪体积分数高的患者，如果脂肪和肌肉的杨氏模量较低，则仰卧位躺在床上时纤维组织因剪切应变损伤的风险增加。

项目成果

Biomechanics Analysis of Pressure Ulcer Using Damaged Interface Model between Bone and Muscle in the Human Buttock

利用人体臀部骨与肌肉损伤界面模型对压疮进行生物力学分析

• DOI: 10.1299/jcst.6.70
• 发表时间: 2012
• 期刊: Journal of Computational Science and Technology
• 作者: Samuel Susanto Slamet;Naoki Takano;Yoshiyuki Tanabe;Asako Hatano and Tomohisa Nagasao
• 通讯作者: Asako Hatano and Tomohisa Nagasao

Monte Carlo simulation highlighting on the tail probability for a dynamic problem

蒙特卡洛模拟强调动态问题的尾部概率

• 发表时间: 2012
• 作者: Sho Suzuki;Naoki Takano;Kota Okamoto and Mitsuteru Asai
• 通讯作者: Kota Okamoto and Mitsuteru Asai

慶應義塾大学形成外科 医学―工学 研究グループ

庆应义塾大学整形外科医学工学研究组

Biomechanics analysis of pressure ulcer using damaged interface model between bone & muscle

利用骨间损伤界面模型对压疮进行生物力学分析

• 发表时间: 2012
• 作者: Samuel Susanto Slamet;Naoki Takano and Tomohisa Nagasao
• 通讯作者: Naoki Takano and Tomohisa Nagasao

Practical Monte Carlo Simulation Method Highlighting on Tail Probability with Application to Biomechanics Analysis of Pressure Ulcer

强调尾部概率的实用蒙特卡罗模拟方法在压疮生物力学分析中的应用

• DOI: 10.11421/jsces.2014.20140001
• 发表时间: 2014
• 期刊: Transactions of the Japan Society for Computational Engineering and Science
• 作者: Samuel Susanto Slamet;Kyohei Hatano;Naoki Takano and Tomohisa Nagasao
• 通讯作者: Naoki Takano and Tomohisa Nagasao