Enhancement of bone conductivity for tailor-made biomedical materials

增强定制生物医学材料的骨传导性

• 批准号: 23792229
• 负责人: NAITO Yoshihito
• 金额: $ 1.91万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23792229/
• 关键词: 生体材料; テーラーメイド医療; チタン; 薬剤徐放担体; 骨補填剤; 骨補填材; 歯学; 薬物徐放担体; 骨代替材

The aim of this study is to develop the drug delivery scaffolds that achieve more stable bone conductivity using the porous titanium which is produced by moldless process and the microsphere capsule which has good controlled-release ability. We have already determined the drug design (the selection of drug, the particle adaptation of microsphere). We will evaluate the way to load of microsphere into the pore of porous titanium and the bone response of it in vivo.

本研究的目的是利用无模成型的多孔钛和具有良好控释能力的微球胶囊，开发具有更稳定骨传导性的药物缓释支架。我们已经确定了药物设计（药物的选择，微球的颗粒适应性）。我们将对微球在多孔钛孔隙中的负载方式及其在体内的骨反应进行评价。

项目成果

Formability and mechanical properties of porous titanium produced by a moldless process.

• DOI: 10.1002/jbm.b.32919
• 发表时间: 2013-08
• 期刊: Journal of biomedical materials research. Part B, Applied biomaterials
• 作者: Yoshihito Naito;Jiyoung Bae;Y. Tomotake;K. Hamada;K. Asaoka;T. Ichikawa

Fabrication of porous titanium using moldless and space holder technique

使用无模和空间保持技术制造多孔钛

• 发表时间: 2013
• 作者: Y. Naito;H. Suito;Jiyoung Bae;K. Hamada;T. Ichikawa
• 通讯作者: T. Ichikawa

スペースホルダー法を用いた医用チタン多孔体の気孔径制御

利用空间保持器法控制医用多孔钛材料的孔径

• 发表时间: 2012
• 作者: Y. Naito;H. Suito;Jiyoung Bae;K. Hamada;T. Ichikawa;兒玉直紀;水頭英樹,内藤禎人,Bae Ji-Young,浜田賢一,市川哲雄
• 通讯作者: 水頭英樹,内藤禎人,Bae Ji-Young,浜田賢一,市川哲雄