Influences of sex hormone and growth factors on craniofacial bone growth

从出生后即刻开始应用于青春期前半期，雌二醇影响ER-β受体为主要过程，并对女性软骨和成骨细胞产生影响，在青春期后半段，ER-α受体活性随年龄增长而升高，提示雌二醇影响ER-α受体为主要过程的可能性。此外，在男性，在青春期的前半段，从出生后立即开始，DHT的产生增加了，而不是E2，而且有一种可能性，即骨骼生长将根据AR受体的进程而增强，因为在青春期的后半段应用了E2，这是使ER-β受体成为主要过程的原因。

It applied in the first half of adolescence from immediately after birth, E2 affect ER-beta Receptor as the main course and it has had influence to a cartilage and osteoblast cells in female, In the second half of adolescence, the activity of ER-alpha Receptor increased with aging, and a possibility that E2 influence ER-alpha Receptor as the main course was suggested. Moreover, in male, in the first half of adolescence from immediately after birth, DHT production increased rather than E2, and a possibility that bone growth would enhancesaccording to the course through AR-Receptor was suggested, having applied E2 in the second half of the adolescence of what makes ER-beta Receptor the main course.