Influences of sex hormone and growth factors on craniofacial bone growth

从出生后即刻起应用于青春期前半期，E2以影响er - β受体为主，对女性软骨和成骨细胞有影响；青春期后半期，er - α受体活性随年龄增长而增加，提示E2可能以影响er - α受体为主。此外，在男性中，从出生后立即开始的青春期的前半期，DHT的产生增加而不是E2，并且根据ar受体的过程，骨骼生长可能会增强，这表明在青春期的后半期应用E2使er - β受体成为主要过程。

It applied in the first half of adolescence from immediately after birth, E2 affect ER-beta Receptor as the main course and it has had influence to a cartilage and osteoblast cells in female, In the second half of adolescence, the activity of ER-alpha Receptor increased with aging, and a possibility that E2 influence ER-alpha Receptor as the main course was suggested. Moreover, in male, in the first half of adolescence from immediately after birth, DHT production increased rather than E2, and a possibility that bone growth would enhancesaccording to the course through AR-Receptor was suggested, having applied E2 in the second half of the adolescence of what makes ER-beta Receptor the main course.