H2CO3 and PRP accelerates tooth movement

H2CO3 和 PRP 加速牙齿移动

• 批准号: 23792445
• 负责人: SATO YUKI
• 金额: $ 2.75万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23792445/
• 关键词: 炭酸ガス

PRP is blood plasma with concentrated platelets. H2CO3 is carbon dioxide. The purpose of this study was to clarify the effect of PRP on tooth movement of rat molar. (Methods) 11week rats. Ni-T closed coil (10g) placed and started tooth movement between U1 to M1 tooth. Rats assigned to the three group; 1-Control rats, 2-PRP rats 3-H2CO3. PRP (0.1ml/100g) or Physiological saline administered to palate when tooth movement starts. Rats fixed after 1, 3 and 7days of tooth movement. uCT taken and observed. The section stained by HE and TRAP, observed by light microscope (Results) PRP accelerated the tooth movement. Acceleration of the tooth movement will not show immediately after PRP administration. There is time difference. H2CO3 no found any significance difference up to 7days for tooth movement PRP accelerates tooth movement due to PRP transiently accelerating the entire alveolar bone resorbing activity but H2CO3 is not accelerating short term tooth movement.

PRP是具有浓缩的血小板的血浆。H_2CO3是二氧化碳。本研究旨在阐明PRP对大鼠磨牙移动的影响。(方法)11周龄大鼠。Ni-T闭合线圈(10g)放置并启动U1至M1牙齿之间的牙齿移动。大鼠分为三组：1-对照组，2-PRP组，3-H_2CO_3组。当牙齿开始移动时，将PRP(0.1ml/100g)或生理盐水注入腭部。大鼠在牙齿移动后1、3、7d固定。UCT采集并观察。苏木精-伊红染色，TRAP染色，光镜下观察。PRP给药后牙齿移动速度不会立即加快。有时差。H_2CO_3对牙齿移动的影响在7天内无显着性差异，但H_2CO_3对牙齿短期移动无明显促进作用。