Clinical application of genetic tests regarding cariogenicity of Streptococcus mutans
Clinical application of genetic tests regarding cariogenicity of Streptococcus mutans
批准号:
23792506
负责人:
KANEKO Noboru
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
An important virulence factor of S. mutans is a glucosyltransferase synthesizing water-insoluble glucan (WIG) from sucrose. We performed sequencing of the gtfB gene of S. mutans isolates derived from primary school students.GtfB coded by gtfB gene possess two functional domain. The carboxyl-terminal portion of GtfB is called the glucan binding domain and is coded by the direct repeating units. The results of this study indicated that the substitution of 33rd amino acid Gly to Ser in the repeating unit is associated with WIG synthesis by S. mutans. And we revealed that the p.G33S substitution is associated with caries development in 1 year in the students using a fluoride mouth rinse.
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口腔乾燥症診断シート導入の試み
尝试推出口干症诊断表
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Ito K, Takamatsu K, Nohno K, Yamada A, Funayama S, Katsura K, Kaneko N, Hatakeyama A, Ogawa M, Inoue M, 伊藤加代子,船山さおり,勝良剛詞,金子昇,濃野要,山田亜紀,井上誠]
通讯作者:
伊藤加代子,船山さおり,勝良剛詞,金子昇,濃野要,山田亜紀,井上誠
Streptococcus mutansのgtfB遺伝子におけるdirect repeatと非水溶性グルカン合成能
变形链球菌gtfB基因的直接重复和合成水不溶性葡聚糖的能力
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Ito K, Takamatsu K, Nohno K, Yamada A, Funayama S, Katsura K, Kaneko N, Hatakeyama A, Ogawa M, Inoue M, 伊藤加代子,船山さおり,勝良剛詞,金子昇,濃野要,山田亜紀,井上誠, 勝良剛詞,伊藤加代子,濃野要,船山さおり,金子昇,山田亜紀,林孝文, 伊藤加代子,濃野要,船山さおり,金子昇,山田亜紀,畠山文,佐々木綾子,井上誠, 金子 昇,濃野 要,葭原明弘,花田信弘,宮﨑秀夫, 金子 昇,花田信弘]
通讯作者:
金子 昇,花田信弘
DOI:
10.1177/0022034512455063
发表时间:
2012-09-01
期刊:
JOURNAL OF DENTAL RESEARCH
影响因子:
7.6
作者:
[Iwasaki, M., Taylor, G. W., Miyazaki, H.]
通讯作者:
Miyazaki, H.
Streptococcus mutansのGtfB酵素C末端側におけるアミノ酸配列と齲蝕との関連性
变形链球菌GtfB酶C端氨基酸序列与龋齿的关系
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Umetsu H, Kaneko N, Yoshihara A, Sakuma S, Hanada N, Miyazaki H, 金子昇,濃野要,葭原明弘,花田信弘,宮﨑秀夫]
通讯作者:
金子昇,濃野要,葭原明弘,花田信弘,宮﨑秀夫
ドライマウス診断におけるpulse Doppler ultrasonographyの可能性
脉冲多普勒超声检查在口干诊断中的潜力
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Ito K, Takamatsu K, Nohno K, Yamada A, Funayama S, Katsura K, Kaneko N, Hatakeyama A, Ogawa M, Inoue M, 伊藤加代子,船山さおり,勝良剛詞,金子昇,濃野要,山田亜紀,井上誠, 勝良剛詞,伊藤加代子,濃野要,船山さおり,金子昇,山田亜紀,林孝文]
通讯作者:
勝良剛詞,伊藤加代子,濃野要,船山さおり,金子昇,山田亜紀,林孝文
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Development of a genetic test for Streptococcus sobrinus
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批准号:26463159
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2014
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负责人:KANEKO Noboru
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依托单位:
The development of genetic tests regarding cariogenicity of mutans streptococci
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批准号:20791635
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.41万
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财政年份:2008
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负责人:KANEKO Noboru
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依托单位:
海外基金