Analysis of Plant Pathogen Resistance Supported by the ER Body

内质网体是拟南芥中积累的一种内质网衍生结构。由于创伤处理诱导了内质网体的产生，因此内质网体参与了植物抵抗昆虫和病原菌攻击的防御系统。两种可溶性蛋白NAI 2和PYK 10以及两种膜整合蛋白MEB 1和MEB 2在ER体中特异性积累，但其功能尚不清楚。我发现NAI 2和PYK 10负责ER体的形成。MEB 1和MEB 2具有铁/锰转运活性，提示ER体参与了抗金属胁迫的过程。这些发现揭示了植物ER体形成和功能的独特机制

Endoplasmic reticulum (ER) body is an ER derived structure that is accumulated in Arabidopsis thaliana. ER body is involved in plant defense system against insect and pathogen attack, since wound treatment induced ER bodies. Two soluble proteins NAI2 and PYK10, and two integral membrane proteins MEB1 and MEB2 are accumulated specifically in ER bodies, but their functions were obscure. I found that NAI2 and PYK10 are responsible for the ER body formation. MEB1 and MEB2 have iron/manganese transport activity, suggesting that ER body is involved in the metal stress resistance. These findings unrevealed unique mechanisms for ER body formation and function in plants