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Screening of anti-virus activities from deep-sea-adapted bacteria

Screening of anti-virus activities from deep-sea-adapted bacteria
筛选适应深海的细菌的抗病毒活性
批准号:
23780198
负责人:
KAWANO Hiroaki
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
We isolated deep-sea-adapted bacteria from deep-sea-mud samples collected at the Japan sea, Sagami bay, and Japan trench. These bacteria were stored as a bacterial library and their diversity was analyzed based on the 16S rDNA nucleotide sequences. One thousand bacteria were cultured and the resulting supernatants were stored so as to be used for anti-virus activity screening. In addition, establishment of EGFP/NLS/NES cell line which will be used for anti-virus activity screening was successfully achieved. Furthermore, we found significant anti-influenza virus activities in13 supernatant mixtures of deep-sea bacterial cultures.
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DOI: 10.5582/ddt.2011.v5.6.286
发表时间: 2011-01-01
期刊: DRUG DISCOVERIES AND THERAPEUTICS
影响因子: 3.1
作者: [Abkallo, Hussein Molu, Kawano, Hiroaki, Kobayashi, Nobuyuki]
通讯作者: Kobayashi, Nobuyuki
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