Spatial regulation of branching tubulogenesis by Wnt signaling
Spatial regulation of branching tubulogenesis by Wnt signaling
批准号:
23790333
负责人:
MATSUMOTO Shinji
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
Novel factor X regulating epithelial branching tubulogenesis induced by Wnt3a and EGF was identified by microarray analysis. Factor X activated Rac and inhibited Rho respectively, resulting in cell extension and ac tivation of cell motility. Cell morphological change induced cell proliferation in three dimensional matrix. These results indicate that Wnt and EGF signaling regulates epithelial branching tubulogenesis cooperatively.
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Wnt3a and Wnt5a regulate epithelial polarity and tubulogenesis cooperatively
Wnt3a 和 Wnt5a 协同调节上皮极性和肾小管发生
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Matsumoto, S., Kikuchi, A.]
通讯作者:
A.
がん生物学イラストレイテッド
癌症生物学图解
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[古賀宣勝, 松村保広]
通讯作者:
松村保広
DOI:
10.1038/ncomms1861
发表时间:
2012-05-01
期刊:
NATURE COMMUNICATIONS
影响因子:
16.6
作者:
[Ishida-Takagishi, Maki, Enomoto, Atsushi, Takahashi, Masahide]
通讯作者:
Takahashi, Masahide
Wnt/β-cateninシグナルとEGFシグナルの協調による三次元基質内での上皮分枝管腔形成制御機構の解析
Wnt/β-catenin信号和EGF信号协调分析三维矩阵内上皮分支管腔形成的控制机制
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Kikuchi A, Yamamoto H, Sato A, Mastumoto S., 松本 真司, Nakagawa T, 松本 真司]
通讯作者:
松本 真司
Wnt/β-catenin シグナルとEGF シグナルの協調による三次元基質内での上皮分枝管腔形成制御機構の解析
通过 Wnt/β-catenin 和 EGF 信号协调控制三维矩阵内上皮分支管腔形成的机制分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Kikuchi A, Yamamoto H, Sato A, Mastumoto S., 松本 真司]
通讯作者:
松本 真司
共 11 条
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批准号:15K13227
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$1.58万
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财政年份:2015
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负责人:MATSUMOTO Shinji
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依托单位:
Wnt signaling promotes epithelial tubulogenesis through the regulation of cell morphology and proliferation
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Development of Teaching-Materials to Enhance Reasoning Skills of Non-Continuous Text for the Integrated Studies
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财政年份:2012
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负责人:MATSUMOTO Shinji
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依托单位:
A Practical Research Introducing Logical Reasoning in Teaching Design and Evaluation Based on "Philosophy for Children" Program
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批准号:21653100
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$1.54万
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财政年份:2009
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负责人:MATSUMOTO Shinji
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依托单位:
Development of Evaluation System for Teaching Materials Using Fuzzy System
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批准号:07808027
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项目类别:Grant-in-Aid for Scientific Research (C)
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财政年份:1995
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负责人:MATSUMOTO Shinji
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依托单位:
海外基金