The promotion of hepatic regeneration by lipid droplet's proteins operation

脂滴代谢是肝脏再生所必需的。这项研究的目的是通过控制蛋白质在LD上的降解来促进肝脏再生。在本研究中，我们发现UBXD8和p97/VCP定位于LDS，并且它们参与了LDS周围的载脂蛋白B的降解。此外，我们还发现UBXD8参与了LD相关蛋白的降解以及LDS中的脂质代谢。对UBXD8的进一步研究应该有助于开发一种促进肝脏再生的新技术。

Lipid droplet metabolism is essential for liver regeneration. The aim of this study is to promote liver regenerationby controlling a degradation of protein on LD. In this study, we found that UBXD8 and p97/VCP are localized on LDs, and that they are engaged in apolipoprotein B degradation around LDs. Furthermore, we showed that UBXD8 participated in degradation of LD-associated proteins as well as lipid metabolism in LDs. Further studies on UBXD8 should help develop a new technique that promotes liver regeneration.