The brain regeneration using chemotactic stimulation with favorable chemoattractant factor for autologous tissue stem cells

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The aim of this project is for regeneration of brain tissue using stem cell migration from undamaged tissue to damaged tissue,that has been implanted high affinity scaffold. We made chemoattractant cocktail for stem cell migration. We confirmed that the cocktail accelerated stem cells migration. And we fabricated nano particles, which can release chemotactic factor long lasting, over 42 days. Finally, we fabricated scaffold. Although the scaffold had appropriate pore size for cell adhesion and growing, scaffold materials had cytotoxicity against stem cells. Cytotoxicity has been improving.