Establishment of detection system of MRD by FACS and analysis of leukemic stem cells in AML
Establishment of detection system of MRD by FACS and analysis of leukemic stem cells in AML
批准号:
23659296
负责人:
ADACHI Souichi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 --
中文摘要
本研究旨在建立一种新的流式细胞术检测儿童急性髓系白血病(AML)细胞微小残留病(MRD)的方法。我们用16种不同的抗体建立了104个细胞中一个细胞的灵敏度的新检测系统。我们在JPLSG临床试验中开始了AML样品的这种测定。
英文摘要
The aim of this study is to establish new flowcytometric assay to detect minimal residual disease(MRD) of acute myeloid leukemia(AML) cells in children. We established this new assay system for sensitivity one cell in 104 cells by using 16 different antibodies. We started this assay for AML samples in JPLSG clinical trials.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1007/s12185-010-0754-y
发表时间:
2011-01-01
期刊:
INTERNATIONAL JOURNAL OF HEMATOLOGY
影响因子:
2.1
作者:
[Ohta, Hideaki, Iwamoto, Shotaro, Komada, Yoshihiro]
通讯作者:
Komada, Yoshihiro
造血器腫瘍学基礎と臨床の最新研究動向
造血肿瘤学基础与临床最新研究动态
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[足立壯一, 他]
通讯作者:
他
FCM-MRD Study in Future AML Clinical Trials by JPLSG
JPLSG 未来 AML 临床试验中的 FCM-MRD 研究
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Watanabe Y, Maekawa M, 岩本彰太郎]
通讯作者:
岩本彰太郎
Establishment of new system for genomic analysis for AML using by desk-top next generation sequencer
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批准号:26670277
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2014
-
负责人:ADACHI Souichi
-
依托单位:
Establishment of new extraction system from bone marrow smear by laser microdissection
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批准号:24659273
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
-
财政年份:2012
-
负责人:ADACHI Souichi
-
依托单位:
Development of new tharapy and search for new cell death mechanism in hematologic malignancies
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批准号:23390273
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.4万
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财政年份:2011
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负责人:ADACHI Souichi
-
依托单位:
Development of new treatment for refractory malignant diseases and investigation of new cell death mechanisms
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批准号:20591254
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:ADACHI Souichi
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依托单位:
New type of cell death mechanism induced by chemotherapeutic agents
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批准号:17591083
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2005
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负责人:ADACHI Souichi
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依托单位:
Anti-tumor effect by non-steroidal anti-inflammatory drugs
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批准号:13670800
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:2001
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负责人:ADACHI Souichi
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依托单位:
海外基金