Search for new disinfectants with marginal tissue-toxicity at the skin care

为了利用精氨酸、氨基酸衍生物和天然食品衍生产品开发安全有效的皮肤护理消毒剂，我们对这些化合物对几种病原微生物的感染性进行了定量表征，并寻找新的具有消毒活性的候选化合物。除了这些体外研究外，我们还进行了一些体内初步研究，以揭示这些化合物在实验动物模型中作为治疗或预防药物对体表浅表病毒感染(如疱疹角膜炎和生殖器疱疹)的有效性。我们还检测了医院用品表面的病毒灭活率。

To develop safe and effective disinfectants for the skin care by the use of arginine, amino acid derivatives and natural food-derived products, we have characterized the effect of these compounds on the infectivity of several pathogenic microbes quantitatively and searched for new candidate compounds with disinfectant activities. In addition to these in vitro studies, we performed some in vivo pilot studies to reveal the effectiveness of these compounds as therapeutic or preventive medicines against the superficial virus infection at the body surface (such as herpetic keratitis and genital herpes) in experimental animal models. We also examined the rate of virus inactivation on the surface of the hospital goods.