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Elucidation of mechanisms for regulating retinal circulation and identification of target molecule for novel preventive and/or therapeutic drugs for retinopathy

Elucidation of mechanisms for regulating retinal circulation and identification of target molecule for novel preventive and/or therapeutic drugs for retinopathy
阐明视网膜循环调节机制并鉴定新型视网膜病预防和/或治疗药物的靶分子
批准号:
24590122
负责人:
ISHII Kunio
金额:
$3.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31

项目摘要

项目成果

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会议论文
網膜循環調節機構の基礎的研究と糖尿病性眼疾患に対する新規予防治療戦略開拓の試み
视网膜循环调节机制基础研究及糖尿病眼病预防治疗新策略的尝试
DOI: --
发表时间:
期刊:
影响因子: --
作者: [安藤眞, 松本貴之, 渡邊駿, 山田浩介, 井口舞香, 鳥羽美貴子, 金津智絵, 新井隆三, 上原千晶, 佐川なつ実, 田口久美子, 小林恒雄, 石井 邦雄]
通讯作者: 石井 邦雄
Impaired retinal vasodilator response to acetylcholine in a rat model of NMDA-induced retinal degeneration.
NMDA 诱导的视网膜变性大鼠模型中视网膜血管舒张剂对乙酰胆碱的反应受损。
DOI: 10.1016/j.jphs.2014.12.014
发表时间: 2015
期刊: J Pharmacol Sci.
影响因子: --
作者: [Mori A, Hanada M, Sakamoto K, Nakahara T, Ishii K.]
通讯作者: Ishii K.
Treatment of Newborn Mice with Inhibitors of Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Induces Abnormal Retinal Vascular Patterning
用血管内皮生长因子受体酪氨酸激酶抑制剂治疗新生小鼠可诱导异常的视网膜血管模式
DOI: 10.1248/bpb.b14-00540
发表时间: 2014
期刊: Biological and Pharmaceutical Bulletin
影响因子: 2
作者: [Morita A, Nakahara T, Ushikubo H, Mori A, Sakamoto K, Ishii K.]
通讯作者: Ishii K.
Elucidation of Dysfunctional Mechanisms of Retinal Circulation in the Rat Models of Glaucoma and Exploration of Novel Therapeutic Drugs
青光眼大鼠模型视网膜循环功能障碍机制的阐明及新型治疗药物的探索
DOI: 10.1248/yakushi.13-00228-2
发表时间: 2013
期刊: YAKUGAKU ZASSHI
影响因子: 0.3
作者: [Mori A, Nakahara T, Kurauchi Y, Sakamoto K, Ishii K.]
通讯作者: Ishii K.
18
    Mechanisms of neuronal-glial-vascular interactions in the retina and the development of novel strategies for treating retinal diseases
    • 批准号:
      16K08554
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2016
    • 负责人:
      ISHII Kunio
    • 依托单位:
    Elucidation of the molecular basis attributed to onset of abnormal retinal hemodynamics and strategy of novel prevention drugs for retinopathy
    • 批准号:
      21590102
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2009
    • 负责人:
      ISHII Kunio
    • 依托单位:
    Development of high-resolution digital fundus camera for small animals and application of it to studies on analysis of responsiveness of retinal blood vessels
    • 批准号:
      12672116
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.5万
    • 财政年份:
      2000
    • 负责人:
      ISHII Kunio
    • 依托单位:
    Studies on responsiveness of rat retial blood vessels with a newly developed digital funduscope system for small animals
    • 批准号:
      10672051
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.11万
    • 财政年份:
      1998
    • 负责人:
      ISHII Kunio
    • 依托单位:
    海外基金