High functionalization of macrocyclic host compounds based on dynamic octadentate cyclen-metal complexes

合成了一系列基于两个八齿环戊二烯金属配合物的大三环主体化合物，并将其应用于利用内腔识别客体阴离子。双核配合物动态地改变其分子结构，这取决于溶剂，侧链和客体分子。特别地，首次通过设计一种钠配合物实现了钠配合物的分子构型。手性二镧系元素配合物对客体阴离子的手性识别是通过镧系元素阳离子发射强度的差异来检测的，在某些情况下，这可以通过肉眼来区分。我们还开发了两种新的方法控制的octadentate cyclen金属配合物的分子动力学：双峰控制的分子动力学，和可逆的分子开关使用有机反应。

A series of macrotricyclic host compounds based on two octadentate cyclen-metal complexes was synthesized and applied for the recognition of guest anions using the internal cavity. The dinuclear complexes dynamically changed their molecular structures depending on solvent, side chains, and guest molecules. Especially, molecular recognitions by sodium complex was firstly achieved by using a sophisticatedly designed disodium complex. Chirality recognition of guest anions by chiral di-lanthanoid complexes was detected by the difference of emission intensity of the lanthanoid cations, which can be distinguished by naked eyes in some cases. We also developed two novel methods for the control of molecular dynamics of octadentate cyclen-metal complexes: a bimodal control of molecular dynamics, and reversible molecular switching using organic reactions.