High functionalization of macrocyclic host compounds based on dynamic octadentate cyclen-metal complexes

基于动态八齿环-金属配合物的大环主体化合物的高功能化

• 批准号: 24750133
• 负责人: ITO Hiroshi
• 金额: $ 2.91万
• 依托单位: Osaka City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24750133/
• 关键词: 超分子化学; 金属錯体; サイクレン; 分子認識; 構造有機化学; キラリティー; ランタノイド; ナトリウム

A series of macrotricyclic host compounds based on two octadentate cyclen-metal complexes was synthesized and applied for the recognition of guest anions using the internal cavity. The dinuclear complexes dynamically changed their molecular structures depending on solvent, side chains, and guest molecules. Especially, molecular recognitions by sodium complex was firstly achieved by using a sophisticatedly designed disodium complex. Chirality recognition of guest anions by chiral di-lanthanoid complexes was detected by the difference of emission intensity of the lanthanoid cations, which can be distinguished by naked eyes in some cases. We also developed two novel methods for the control of molecular dynamics of octadentate cyclen-metal complexes: a bimodal control of molecular dynamics, and reversible molecular switching using organic reactions.

合成了一系列基于两个八齿环戊二烯金属配合物的大三环主体化合物，并将其应用于利用内腔识别客体阴离子。双核配合物动态地改变其分子结构，这取决于溶剂，侧链和客体分子。特别地，首次通过设计一种钠配合物实现了钠配合物的分子构型。手性二镧系元素配合物对客体阴离子的手性识别是通过镧系元素阳离子发射强度的差异来检测的，在某些情况下，这可以通过肉眼来区分。我们还开发了两种新的方法控制的octadentate cyclen金属配合物的分子动力学：双峰控制的分子动力学，和可逆的分子开关使用有机反应。

项目成果

Chirality Transfer in Propeller-Shaped Cyclen―Calcium(II) Complexes: Metal-Coordinating and Ion-Pairing Anion ProtocolsProcedures

螺旋桨状 Cyclen—钙 (II) 配合物中的手性传递：金属配位和离子对阴离子方案程序

• DOI: 10.1002/chem.201204323
• 发表时间: 2012
• 期刊: Chemistry -A European Journal
• 作者: Hiroshi Ito;Hiroshi Tsukube;Satoshi Shinoda
• 通讯作者: Satoshi Shinoda

A chirality rewriting cycle mediated by a dynamic cyclen-calcium complex.

• DOI: 10.1039/c2cc35350d
• 发表时间: 2012-10
• 期刊: Chemical communications
• 影响因子: 4.9
• 作者: Hiroshi Ito;H. Tsukube;S. Shinoda

Publication

• DOI: 10.1007/bf03191973
• 发表时间: 2010
• 期刊: Mycotoxin Research
• 影响因子: 3

機能化学研究室

功能化学实验室

Chirality Transfer in Propeller-Shaped Cyclen–Calcium(II) Complexes : Metal-Coordinating and Ion-Pairing Anion Procedures

螺旋桨状 Cyclen-钙 (II) 配合物中的手性传递：金属配位和离子对阴离子程序

• 发表时间: 2013
• 期刊: Chem.–Eur. J.
• 作者: Ito;H.; Tsukube;H.; Shinoda;S.
• 通讯作者: S.