Promotion Mechanism and Factor in Lactic Acid-Fermented Soymilk on the Gene Expression of Cyp7a1

近年来高脂血症的发病率有所增加。有人认为豆浆可以预防高脂血症。我们证实，发酵豆乳具有脂质代谢调节作用，从而促进胆固醇分解代谢相关基因的表达。因此，我们研究了乳酸发酵豆乳中的脂质代谢调节因子，乳酸发酵豆乳中的异黄酮由糖基转化为糖苷基，似乎可以促进肠道吸收。因此，这表明，发酵豆乳含有高比例的阿拉伯糖基可能会促进脂质代谢的调节作用和Cyp7a1的基因表达。

The incidence of hyperlipidemia has increased in recent years. It has been suggested that soymilk can prevent hyperlipidemia. We confirmed that fermented soymilk has lipid metabolism-modulating effects whereby it promotes cholesterol catabolism-related gene expression. Thus, we investigated the lipid metabolism-modulating factor in lactic acid-fermented soymilk.Isoflavone in fermented soymilk converted from glycone to aglycone by lactic acid fermentation appears to promote intestinal absorption. Thus, it is suggested that fermented soymilk containing a high ratio of isoflavone aglycone may promote lipid metabolism-modulating effects and the gene expression of Cyp7a1.