Analysis of cancer attractors on gene expression potentials by gene-environment (GxE) interactions

通过基因-环境 (GxE) 相互作用分析癌症吸引子对基因表达潜力的影响

• 批准号: 25330333
• 负责人: OGISHIMA Soichi
• 金额: $ 3.08万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25330333/
• 关键词: 生命情報; 癌アトラクター; 疾患アトラクター; 遺伝子-環境相互作用; GxE

项目成果

細胞の分化・誘導に関わる発現ポテンシャル解析

与细胞分化/诱导相关的表达电位分析

• 发表时间: 2013
• 作者: 荻島創一;田中博
• 通讯作者: 田中博

The statistical geometry of transcriptome divergence in cell-type evolution and cancer

• DOI: 10.1038/ncomms7066
• 发表时间: 2015-01-01
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Liang, Cong;Forrest, Alistair R. R.;Wagner, Guenter P.
• 通讯作者: Wagner, Guenter P.

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

• DOI: 10.1126/science.1259418
• 发表时间: 2015-02-27
• 期刊: Science (New York, N.Y.)
• 作者: Arner E;Daub CO;Vitting-Seerup K;Andersson R;Lilje B;Drabløs F;Lennartsson A;Rönnerblad M;Hrydziuszko O;Vitezic M;Freeman TC;Alhendi AM;Arner P;Axton R;Baillie JK;Beckhouse A;Bodega B;Briggs J;Brombacher F;Davis M;Detmar M;Ehrlund A;Endoh M;Eslami A;Fagiolini M;Fairbairn L;Faulkner GJ;Ferrai C;Fisher ME;Forrester L;Goldowitz D;Guler R;Ha T;Hara M;Herlyn M;Ikawa T;Kai C;Kawamoto H;Khachigian LM;Klinken SP;Kojima S;Koseki H;Klein S;Mejhert N;Miyaguchi K;Mizuno Y;Morimoto M;Morris KJ;Mummery C;Nakachi Y;Ogishima S;Okada-Hatakeyama M;Okazaki Y;Orlando V;Ovchinnikov D;Passier R;Patrikakis M;Pombo A;Qin XY;Roy S;Sato H;Savvi S;Saxena A;Schwegmann A;Sugiyama D;Swoboda R;Tanaka H;Tomoiu A;Winteringham LN;Wolvetang E;Yanagi-Mizuochi C;Yoneda M;Zabierowski S;Zhang P;Abugessaisa I;Bertin N;Diehl AD;Fukuda S;Furuno M;Harshbarger J;Hasegawa A;Hori F;Ishikawa-Kato S;Ishizu Y;Itoh M;Kawashima T;Kojima M;Kondo N;Lizio M;Meehan TF;Mungall CJ;Murata M;Nishiyori-Sueki H;Sahin S;Nagao-Sato S;Severin J;de Hoon MJ;Kawai J;Kasukawa T;Lassmann T;Suzuki H;Kawaji H;Summers KM;Wells C;FANTOM Consortium;Hume DA;Forrest AR;Sandelin A;Carninci P;Hayashizaki Y
• 通讯作者: Hayashizaki Y

BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains.

• DOI: 10.1186/2041-1480-5-5
• 发表时间: 2014-02-05
• 期刊: Journal of biomedical semantics
• 影响因子: 1.9
• 作者: Katayama T;Wilkinson MD;Aoki-Kinoshita KF;Kawashima S;Yamamoto Y;Yamaguchi A;Okamoto S;Kawano S;Kim JD;Wang Y;Wu H;Kano Y;Ono H;Bono H;Kocbek S;Aerts J;Akune Y;Antezana E;Arakawa K;Aranda B;Baran J;Bolleman J;Bonnal RJ;Buttigieg PL;Campbell MP;Chen YA;Chiba H;Cock PJ;Cohen KB;Constantin A;Duck G;Dumontier M;Fujisawa T;Fujiwara T;Goto N;Hoehndorf R;Igarashi Y;Itaya H;Ito M;Iwasaki W;Kalaš M;Katoda T;Kim T;Kokubu A;Komiyama Y;Kotera M;Laibe C;Lapp H;Lütteke T;Marshall MS;Mori T;Mori H;Morita M;Murakami K;Nakao M;Narimatsu H;Nishide H;Nishimura Y;Nystrom-Persson J;Ogishima S;Okamura Y;Okuda S;Oshita K;Packer NH;Prins P;Ranzinger R;Rocca-Serra P;Sansone S;Sawaki H;Shin SH;Splendiani A;Strozzi F;Tadaka S;Toukach P;Uchiyama I;Umezaki M;Vos R;Whetzel PL;Yamada I;Yamasaki C;Yamashita R;York WS;Zmasek CM;Kawamoto S;Takagi T
• 通讯作者: Takagi T

Network biology approach to epithelial-mesenchymal transition in cancer metastasis: three stage theory.

• DOI: 10.1093/jmcb/mjv035
• 发表时间: 2015-06
• 期刊: Journal of molecular cell biology
• 影响因子: 5.5
• 作者: Hiroshi Tanaka;S. Ogishima